Background/Objectives: Since non-invasive implants and invasive implants (metastases) are a key point of differentiation between serous borderline tumors (SBTs) and low-grade serous carcinoma (LGSC), the correct diagnosis of these two types…
Endometriosis is a gynecological disease affecting more than 190 million women of reproductive age worldwide, characterized by a complex molecular pathophysiology encompassing genetic, epigenetic, inflammatory, and immunological components.…
Aim of the study. To study the morphological structure of scar tissue in patients with uterine scar defects (USD) after cesarean section (CS), as well as the effect of changes in mechanical stress in the area of the newly formed scar after …
Background/Objectives: Rarely, primary (PriCs) or metastatic (metECs) carcinomas occur in the episiotomy site. Methods: A systematic literature review of metECs was carried out. We reviewed the PRISMA guidelines and the Scopus, Pubmed, and …
The article focuses on the of methods for objectifying pain syndrome in patients with endometriosis. Endometriosis-related pain, including dysmenorrhea, dyspareunia, and chronic pelvic pain, is a clinically significant symptom of the diseas…
Episiotomy is a perineal incision enlarging the vaginal opening during labor, preventing severe perineal/vaginal/ano-rectal lacerations. We performed a systematic literature review (PRISMA guidelines; Pubmed, Scopus and Web of Science datab…
Objective. Optimization of diagnostic methods for studying the myometrium in adenomyosis using magnetic resonance imaging (MRI) and subsequent construction of a three-dimensional model of the uterus using computer-assisted technologies to o…
Objective. Analysis of immunohistochemical expression of β1- and β2-adrenergic receptors (ADRB1 and ADRB2) in adenomyotic tissues in reproductive-age patients. Material and methods. The study included histological preparations and paraffin …
This review evaluates the advances in the early detection and diagnosis of endometrial cancer (EC), emphasizing the growing importance of minimally invasive techniques and novel biomarkers. Current diagnostic protocols for EC rely heavily o…
Aim. To identify clinical and history features of patients with recurrent deep endometriosis (RDE). Materials and methods. A retrospective study of clinical and history data of 200 patients with DE undergoing surgical treatment at the Depar…
Background. Epithelial-mesenchymal transition (EMT) is a conserved mechanism in the process of morphogenesis and organogenesis. EMT provides cells with migratory and invasive properties, which is a necessary condition for the formation of e…
- 1 .., 1 .., 2 .., 1 .., 1 .., 3 .., 1 .., 1 .., 1,2 \ ..immunohistochemical method and evaluation of the H-score index.When the intensity of zinc finger E-box binding homeobox 1 staining in the endometrium was measured, it was revealed th…
Abstract: Endometriosis is a common gynecological condition characterized by the presence of endometrial-like tissue outside the uterus, causing chronic pelvic pain, dysmenorrhea, and infertility. Recent studies highlight the significant ro…
BACKGROUND: The early diagnosis of endometriosis in adolescents is not developed. OBJECTIVE: We aim to conduct clinical, imaging, laparoscopic and histological analyses of peritoneal endometriosis (PE) in adolescents in order to improve ea…
Aim. To study the regulation of apoptosis in the endometrium of women with chronic endometritis (CE) and external genital endometriosis (EGE) based on the study of the expression of its regulators such as transcription factor (NF-), Bcl-2 a…
Objective. To study the expression of progesterone receptor isoform B (PR-B) in patients with deep infiltrating endometriosis (DIE). Patients and methods. This article presents a comparative analysis of PR-B expression in eutopic and ectopi…
Aim. To analyze the profile of anti-Mllerian hormone (AMH) and the expression level of the transmembrane AMH receptor type II (AMHRII) in the eutopic and ectopic endometrium of patients with deep infiltrative endometriosis (DIE). Materials…
Disruption of endometrial regeneration, fibrosis formation, and intrauterine adhesions underlie the development of "thin" endometrium and/or Asherman's syndrome (AS) and are a common cause of infertility and a high risk for adverse obstetri…
В обзоре представлена сравнительная характеристика эндометриоза и злокачественных опухолей с учетом актуализации классификаций опухолей яичников, рассмотрены факторы риска, морфологическая картина, специфические признаки атипичного эндомет…
Objective of the study is to еvaluate the expression of EphA1 in the endometrium of healthy women, in eutopic and ectopic epithelial cells in deep infiltrative endometriosis. Used materials and methods such as IHC was carried out a comparat…
Uterine leiomyomas usually arise from the uterine body (95%), and rarely from the cervix (0.6%) or other urogenital sites. Lipoleiomyomas are benign, uncommon variants of leiomyomas (0.03-0.2%), histologically composed of smooth muscle cell…