Viktor E. Radzinsky

Endometriosis still remains one of the most interesting but poorly understood disease entities in the world. The current epidemiological research data demonstrate that the endometriosis incidence rate will soon become somewhat of a pandemic…

The search for approaches to diagnosing and treating endometriosis remains a priority in modern gynecology. The extremely high prevalence of this condition and its detrimental effect on somatic and reproductive health and the quality of lif…

Introduction. Long-term chronic inflammation in the endometrium leads to sclerotic changes, disorders in the extracellular matrix and intercellular interactions, and, ultimately, to impaired formation of spiral arteries and hypoperfusion. T…

The global relevance of endometriosis as one of the most common gynaecological nosologies is increasing every year. Currently available evidence-based data help to uncover the most intimate pathogenetic stigmas of the disease and identify k…

Endometriosis is still one of the most mysterious and urgent gynecological diseases. The prevalence of endometriosis is steadily increasing, despite the development of innovative methods of diagnosis and treatment. Endometriosis is the pres…

Aim.To prove the safety and efficacy of using the ultrasonic cavitation of saline to restore the endometrial receptivity, local immune balance, and antioxidant status in females with chronic endometritis (CE) and a history of reproductive l…

Objective. To study the effectiveness of therapy with dienogest (Zafrilla) in the prevention of ovarian endometriosis recurrence after surgical treatment. Patients and methods. This prospective observational comparative study enrolled 104 p…

Objective. Analytical review of the literature on endometriosis-associated infertility, its mechanisms and hormone therapy in preparation for in vitro fertilization (IVF). Endometriosis is considered the most common benign but potentially m…

OBJECTIVE: To review the mechanisms of endometriosis development, including those related to epigenetic mutations, cellular dysregulation, inflammatory processes, and oxidative stress. METHODS: A systematic literature review regarding curre…

Background. Endometriosis is a chronic progressive recurrent disease associated with pelvis pain, menses disorders and infertility. The prevalence of endometriosis (EGE) tends to increase steadily and reaches 15% among women of reproductive…

Uterine leiomyoma, along with endometriosis, occupies a leading position in the structure of gynecological diseases associated with hyperproliferation. The disease can negatively affect the reproductive potential, gynecological health, soma…

OBJECTIVE: To compare the effectiveness of two different treatment regimens of dydrogesterone in the management of endometriosis-related chronic pelvic pain. DESIGN: Observational, prospective cohort study over six months. SETTING: Twenty g…

Aim. To assess the efficacy and safety of 24-week therapy with dienogest in patients with endometriosis-associated pelvic pain resistant to surgical treatment. Materials and methods. The study included 126 patients aged 3340 years with exte…

The article highlights modern ideas about the role of the endometrium in the genesis of reproductive failures. A crucial place of chronic endometritis in the structure of the endometrial infertility factor in endometriosis is noted. Given t…

Endometriosis is a disease that has a profound impact on the quality of life of women, due to the associated chronic pelvic pain, dysmenorrhea, dyspareunia and infertility. However, even getting long-awaited pregnancy (often after assisted …

OBJECTIVE: The aim of the study was to expand the understanding of pathogenesis of adenomyosis-associated pelvic pain. MATERIAL AND METHODS: We studied 30 (n = 30) biopsy samples obtained after hysterectomy in women with diffuse adenomyosis…

Aim Endometriosis is one of the most common gynecological diseases diagnosed in almost 70% of patients with chronic pelvic pain (CPP). However, a quarter of women with pelvic pain is diagnosed with external genital endometriosis (EGE) durin…

Chronic endometritis (CE) is defined as a state of inflammation localized in the endometrium, accompanied by edema, dissociated maturation of epithelial cells and fibroblasts, increased stromal density and the presence of plasma cell infilt…

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