Hasegawa A

No ORCID on file · 14 papers in corpus · active 2007-2025

Study types

  • article 11
  • other 2

Condition tags

  • endometriosis 13
  • endometrioma 3
  • infertility 1
2025
Gynecology and Minimally Invasive Therapy ·doi:10.4103/gmit.gmit_60_24

ObjectivesThis study aimed to demonstrate the utility of origami crane training in enhancing laparoscopic skills.Materials and methodsThis retrospective study was conducted at our hospital and involved a single participant: a gynecologist q…

other 2017
Human fertility (Cambridge, England) ·doi:10.1080/14647273.2016.1255786

We examined the prognostic factors for pregnancy in 210 vitrified-warmed embryo transfer (ET) cycles in 121 patients. The univariate analysis showed that age, gravida, the number of cycles associated with infertility caused by endometriosis…

article 2016
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12540

PROBLEM: Neutrophils are known to be accumulated in endometriosis; however, direct evidence of the impact of neutrophils in the development of endometriosis was lacking. To clarify the importance of neutrophils, we examined the effect of ne…

article 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.03.023

ObjectiveTo investigate the in vitro effect of drospirenone on human eutopic endometrial (EuSC) and ectopic endometriotic stromal cells (EcSC).DesignComparative and laboratory study. The experimental procedures were approved by the Institut…

article 2013
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2012-3475

CONTEXT: Endometriosis is a chronic inflammatory disease in which immune response and production of estrogen in endometriotic tissues are involved in the development of the disease. Prostaglandin E2 (PGE2) stimulates aromatase (P450arom) ex…

article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.07.1117

ObjectiveTo investigate a new role of interleukin (IL)-17A in endometriosis.DesignLaboratory study.SettingUniversity hospital.Patient(s)Patients with ovarian endometrioma undergoing laparoscopy or laparotomy.Intervention(s)Primary culture o…

article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.04.060

ObjectiveTo examine the effects of interleukin (IL)-17F on the secretion of IL-8 and the gene expression of cyclooxygenase 2 (COX2) in endometriotic stromal cells.DesignIn vitro experimental study using human samples.SettingUniversity hospi…

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.02.053

In an animal endometriosis model, the administration of hyaluronic acid (HA) reagent significantly suppressed the formation of endometriotic lesions in both number and weight. This effect was found when HA treatment was conducted at the tim…

article 2008
The American journal of pathology ·doi:10.2353/ajpath.2008.080527

Endometriosis is a common gynecological disease that affects approximately 10% of women of childbearing age. It is characterized by endometrial growth outside the uterus and often results in inflamed lesions, pain, and reduced fertility. Al…

article 2008
The American journal of pathology ·doi:10.2353/ajpath.2008.071044

Several lines of evidence indicate that the Th2 immune response is associated with endometriosis. Although an increased concentration of interleukin (IL)-4, a typical Th2 cytokine, has been reported in endometriotic tissues, the implication…

article 2008
Human Reproduction ·doi:10.1093/humrep/den385

BACKGROUND: The increase in concentration of osteoprotegerin, an antagonist of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), in the peritoneal fluid of women with endometriosis may interfere with TRAIL-induced apoptosis i…

article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.05.051

The concentration of the soluble form of CD44, a competitive inhibitor for CD44 and hyaluronic acid binding, is higher in the peritoneal fluid of patients with endometriosis than in the peritoneal fluid of patients without endometriosis.

article 2007
Endocrinology ·doi:10.1210/en.2007-0749

IL-17A is secreted from Th17 cells, a discovery leading to revision of the mechanism underlying the role of Th1/Th2 in the immune response. Strong evidence suggests that immune responses associated with inflammation are involved in the path…

article 2007
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2006-2486

CONTEXT: Metformin, a widely used treatment for diabetes that improves insulin sensitivity, also has both antiinflammatory properties and a modulatory effect on ovarian steroid production, two actions that have been suggested to be efficaci…