Edgardo Somigliana

No ORCID on file · 315 papers in corpus · active 1995-2026

Study types

  • article 150
  • review 79
  • other 46
  • letter 16
  • meta-analysis 11

Condition tags

  • endometriosis 283
  • infertility 53
  • endometrioma 37
  • chronic_pelvic_pain 28
  • adenomyosis 28
  • dysmenorrhea 16
  • dyspareunia 16
  • bowel_endometriosis 13
  • die_deep_infiltrating 8
  • bladder_endometriosis 6
review 2016
Seminars in reproductive medicine ·doi:10.1055/s-0036-1597125

The management of endometriosis-related infertility remains debated. However, in recent years, the role of in vitro fertilization (IVF) has progressively grown. Reasons to explain this change include (1) the improvement of the effectiveness…

article 2016

background: There is growing and consistent evidence showing that ovarian reserve is affected following surgical excision of ovarian endometriomas. Of particular concern is the risk of severe ovarian damage leading to unresponsiveness to ov…

article 2016

Ovarian endometriomas are found in a consistent proportion of patients with endometriosis and are associated with a more severe form of the disease. The endometriotic tissue lining the inside of the endometrioma has been extensively studied…

editorial 2016
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2016.03.030
article 2016
Human Reproduction ·doi:10.1093/humrep/dew210

STUDY QUESTION: Are women with endometriosis who conceive with IVF at increased risk of preterm birth? SUMMARY ANSWER: Women with endometriosis who conceive with IVF do not face an increased risk of preterm birth. WHAT IS KNOWN ALREADY: The…

article 2016

The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation

article 2016

Women with endometriosis have a substantial increase in risk of deep dyspareunia with respect to the general female population of corresponding age. This symptom has personal and intimate implications, including unfavorable emotional impact…

article 2016

Ovarian endometriomas are found in a consistent proportion of patients with endometriosis and are associated with a more severe form of the disease. The endometriotic tissue lining the inside of the endometrioma has been extensively studied…

other 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.03.047

OBJECTIVE: To evaluate whether women with endometriosis achieving singleton pregnancies with IVF face an increased risk of miscarriage. DESIGN: Matched case-control study. SETTING: Infertility units. PATIENT(S): Women achieving singleton…

review 2016
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2016.07.513
article 2016
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.15955

The IDEA (International Deep Endometriosis Analysis group) statement is a consensus opinion on terms, definitions and measurements that may be used to describe the sonographic features of the different phenotypes of endometriosis. Currently…

other 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.03.013

OBJECTIVE: To evaluate the accuracy of antral follicular count (AFC) in predicting ovarian responsiveness in ovaries with endometriomas or with a past history of surgical excision of endometriomas. DESIGN: Retrospective review. SETTING: A…

article 2015
Human Reproduction ·doi:10.1093/humrep/dev078

The increasing confidence with the techniques of oocyte and ovarian cortex freezing has prompted their potential use for patient categories other than those at risk of early menopause due to cancer treatments. Women affected by every iatrog…

article 2015
Nutrients ·doi:10.3390/nu7125516

A comprehensive analysis of the vitamin D status of infertile women is the first step in understanding hypovitaminosis impact on reproductive potential. We sought to determine vitamin D profiles of women attending an infertility center and …

article 2015
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2015.01.021
article 2015
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.12647

OBJECTIVE: To evaluate whether iron contained in ovarian endometriomas can diffuse through the cyst wall and negatively affect ovarian function. DESIGN: Prospective case series. SETTING: Infertility unit in an academic setting. POPULATION: …

article 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.11.016
article 2015

Laparoscopic treatment for endometriosis-associated infertility is gaining widespread popularity supported mostly by uncontrolled studies, but the purported benefit of surgery may be overvalued. We have therefore analysed the best available…

article 2015

table of contents † Endometriomas and ovarian responsiveness † Endometrioma-related impact on ovarian responsiveness: a primary or a secondary event? † Treatment prior to IVF † The risks of surgery or expectant management

review 2015
Human reproduction update ·doi:10.1093/humupd/dmv012

BACKGROUND: Classical surgical management of endometriotic ovarian cysts using the laparoscopic stripping technique has been recently questioned because of the surgical-related injury to the ovarian reserve. Accordingly, available guideline…

review 2015
Expert opinion on drug safety ·doi:10.1517/14740338.2016.1121991

INTRODUCTION: All medical treatments for endometriosis are equally effective in relieving pain. However, all of them alleviate pain symptoms for as long as they are used, but pain always relapses when medication is discontinued. Therefore, …

article 2015

BACKGROUND: Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis potentially contri-buting to the pathogenesis of endometriosis. The aim of this study was to investigate the potential association between the single…

review 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.08.003

Deep endometriosis is a demanding condition that is associated with infertility. However, evidence supporting a direct link between deep endometriosis and infertility is weak. In fact, infertility in affected patients is more likely to be e…

review 2015
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1111329

Vitamin D is a fat-soluble pro-hormone that plays an important role in bone homeostasis; beside this principal function, vitamin D promotes modulation of cell growth, neuromuscular and immune function, and reduction of inflammation. In addi…

other 2015
BMC women's health ·doi:10.1186/s12905-015-0248-4

BACKGROUND: Patients, now generally well informed through dedicated websites and support organizations, are beginning to look askance at clinical experimentation. We conducted a survey investigation to verify whether women with endometriosi…