Mekan R. Orazov

There is a statistically significant difference in the frequency of implantation in the group of patients with endometriosis associated with infertility compared with the control group. This has been confirmed by a number of different studi…

Background. Endometriosis is a chronic progressive recurrent disease associated with pelvis pain, menses disorders and infertility. The prevalence of endometriosis (EGE) tends to increase steadily and reaches 15% among women of reproductive…

The review summarizes current understanding of the pathogenesis of ovarian endometriosis and the mechanisms of formation of infertility associated with ovarian endometriosis, as well as the possibilities of treating ovarian endometriosis an…

Aim. To assess the efficacy and safety of using the homeopathic drug Mastopol for the relief of mastalgia in women with infertility, including those associated with endometriosis, as well as to study the drug tolerability and adherence to t…

Study Objective: To expand the idea of the pathogenesis of implantation incompetence of endometrium in women with endometriosis-associated infertility. Study Design: open perspective comparative study. Materials and Methods. The study enrol…

This review aims to explore existing literature surrounding the pathogenic mechanisms causing inflammation in the eutopic endometrium of women with endometriosis-associated infertility. We discuss morphological and functional changes in the…

OBJECTIVE: To compare the effectiveness of two different treatment regimens of dydrogesterone in the management of endometriosis-related chronic pelvic pain. DESIGN: Observational, prospective cohort study over six months. SETTING: Twenty…

Aim. Is specification of the nature and frequency of concomitant forms of genital endometriosis and other estrogen-dependent diseases (EDD) for the infertile women with severe peritoneal endometriosis (PE), as well as the assessment of the …

Aim. To assess the efficacy and safety of 24-week therapy with dienogest in patients with endometriosis-associated pelvic pain resistant to surgical treatment. Materials and methods. The study included 126 patients aged 3340 years with exte…

Numerous studies on animal models endow prolactin with multiple functions, both physiological (reproduction, lactation, growth, metabolism, transport and electrolyte behaviour) and pathological (immunity and carcinogenesis). Prolactin is an…

The article highlights modern ideas about the role of the endometrium in the genesis of reproductive failures. A crucial place of chronic endometritis in the structure of the endometrial infertility factor in endometriosis is noted. Given t…

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BACKGROUND Despite numerous studies and a not decreasing amount of endometriosis and associated infertility, the study of endometriosis- associated infertility does not lose its relevance, and the characteristics of the endometrium is appea…

This review summarizes current understanding of the pathogenesis of one of the most common forms of external genital endometriosis ovarian endometriomas. Due to their frequent occurrence in young women of reproductive age and extremely nega…

The article summarizes the current understanding of risk factors and mechanisms of ovarian endometriosis relapses, This article summarizes the current understanding of risk factors for relapse, mechanisms of recurrence of endometrioid ovar…

This article discusses the causes and mechanisms of the occurrence of infertility in endometriosis within the framework of versions and contraversions. The magnitude of the described problem is noted not only from a medical, but also from a…

Endometriosis is currently considered as one of the most common diseases associated with infertility. A controversial issue is whether endometriosis per se exerts a detrimental effect on IVF outcomes. Failure of implantation due to endometr…

The mechanisms of endometriosis-related infertility remain still unknown. Endometriosis and clinical markers of oocyte quality are a very important problem of reproduction. The purpose of the study is to assess the quality of oocytes in wom…

Выявленные изменения показывают смещение пролиферативно-апоптотического индекса в сторону снижения активности апоптоза в клетках эутопического и эктопического эндометрия при диагностированном дефиците 25(ОН)D.

Relevance. Despite lots of studies, issues on a choice of the most effective treatment method for patients with recurrent external genital endometriosis (EGE) as well as a role and features of assisted reproductive technology programs and w…

Luteal phase deficiency (LPD) is described as a condition of insufficient progesterone exposure to maintain a regular secretory endometrium and allow for normal embryo implantation and growth. There is evidence that both follicular and lute…

The aim of the study was to evaluate the severity of pain syndrome and depression syndrome in women with endometriosis- associated pelvic pain. Materials and methods . The study included 100 women of reproductive age with external genital e…

Methods. For morphological studies it were using fragments of walls 60 uterus, received after hysterectomy in patients with pelvic pain on a background of diffuse adenomyosis II-III degree, and 30 uterus of women with painless form of adeno…