Jacques Donnez

No ORCID on file · 262 papers in corpus · active 1982-2026

Study types

  • article 160
  • review 49
  • other 22
  • letter 11
  • book-chapter 7

Condition tags

  • endometriosis 205
  • adenomyosis 35
  • infertility 34
  • dyspareunia 13
  • dysmenorrhea 12
  • endometrioma 10
  • chronic_pelvic_pain 9
  • bowel_endometriosis 5
  • bladder_endometriosis 1
article 2020
Linzagolix for Endometriosis-Associated Pain: Lipid Changes After 52 Weeks of Treatment [25B]
·doi:10.1097/01.aog.0000663180.46470.c9

INTRODUCTION: Linzagolix is a new, investigational, non-peptide, GnRH receptor antagonist being developed to treat endometriosis-associated pain (EAP). The EDELWEISS trial was a Phase 2b, double-blind, randomized, placebo-controlled, multic…

article 2020
Quality of Life Results After 52 Weeks of Treatment With Linzagolix for Endometriosis-Associated Pain [30B]
·doi:10.1097/01.aog.0000663200.75027.38

INTRODUCTION: Linzagolix is a new investigational, non-peptide, oral GnRH receptor antagonist being developed to treat endometriosis-associated pain (EAP). The EDELWEISS trial was a Phase 2b, double-blind, randomized, placebo-controlled, mu…

article 2020
Treatment of endometriosis-associated pain with linzagolix, an oral gonadotropin-releasing hormone–antagonist: a randomized clinical trial
Fertility and sterility ·doi:10.1016/j.fertnstert.2020.02.114
article 2019
Reprint of: Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities
Fertility and sterility ·doi:10.1016/j.fertnstert.2019.08.081
editorial 2019
What if deep endometriotic nodules and uterine adenomyosis were actually two forms of the same disease?
Fertility and sterility ·doi:10.1016/j.fertnstert.2018.12.018
article 2018
Introduction
Fertility and sterility ·doi:10.1016/j.fertnstert.2018.01.035
article 2018
Invasion of human deep nodular endometriotic lesions is associated with collective cell migration and nerve development
Fertility and sterility ·doi:10.1016/j.fertnstert.2018.08.016
review 2018
Ovarian endometriosis and fertility preservation: a challenge in 2018
Minerva ginecologica ·doi:10.23736/s0026-4784.18.04229-6

Endometriosis is a benign, estrogen-dependent gynecological disorder. It is now well established that three different forms of endometriosis can occur in the pelvic cavity, namely peritoneal endometriosis, ovarian endometriosis and deep end…

editorial 2018
Ovarian endometriosis and infertility: in vitro fertilization (IVF) or surgery as the first approach?
Fertility and sterility ·doi:10.1016/j.fertnstert.2018.10.003
review 2018
Pathogenesis of uterine adenomyosis: invagination or metaplasia?
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.12.030
other 2018
Safety of ovarian tissue transplantation in patients with borderline ovarian tumors
Human Reproduction ·doi:10.1093/humrep/dex352

STUDY QUESTION: Is transplantation of cryopreserved ovarian tissue from patients with borderline ovarian tumors (BOTs) a safe procedure? SUMMARY ANSWER: BOT cells were found in frozen-thawed and xenografted ovarian tissue in 1 of 11 BOT pa…

article 2018
Table of Contents
·doi:10.1016/s0015-0282(18)30247-4
editorial 2018
Women with endometrioma-related infertility face a dilemma when choosing the appropriate therapy: surgery or in vitro fertilization
Fertility and sterility ·doi:10.1016/j.fertnstert.2018.10.002
letter 2017
Endometriosis and risk of embryonic aneuploidy?
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.06.019
article 2017
Endometriosis is associated with aberrant metabolite profiles in plasma
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.12.032
other 2017
Gynecological and obstetrical outcomes after laparoscopic repair of a cesarean scar defect in a series of 38 women
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.09.033

OBJECTIVE: To evaluate gynecological and obstetrical outcomes, as well as remaining myometrial thickness, after laparoscopic repair of a cesarean scar. DESIGN: Observational study and prospective evaluation of the remaining myometrium befo…

article 2017
Important role of collective cell migration and nerve fiber density in the development of deep nodular endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.01.005
other 2017
Introduction: From pathogenesis to therapy, deep endometriosis remains a source of controversy
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.10.015

Deep endometriosis remains a source of controversy. A number of theories may explain its pathogenesis and many arguments support the hypothesis that genetic or epigenetic changes are a prerequisite for development of lesions into deep endom…

letter 2017
Partial suppression of estradiol: a new strategy in endometriosis management?
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.01.013
review 2016
Endometriosis and infertility
Panminerva medica

Endometriosis remains a very enigmatic and perplexing disease. The exact mechanism by which endometriosis causes infertility is still unclear. In the present paper, we will review possible mechanisms leading to subfertility or infertility i…

review 2016
Oxidative stress in the pelvic cavity and its role in the pathogenesis of endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.07.1075
review 2016
Targeting mast cells: a new way to treat endometriosis
Expert opinion on therapeutic targets ·doi:10.1080/14728222.2017.1260548

INTRODUCTION: Endometriosis is a chronic estrogen-dependent inflammatory disease of unclear etiology that affects 15-20% of women of reproductive age. Efforts are now focusing on understanding new mechanisms involved in its physiopathology,…

article 2015
Invasion process of induced deep nodular endometriosis in an experimental baboon model: similarities with collective cell migration?
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.05.011
letter 2015
Microscopic endometriosis: impact on our understanding of the disease and its surgery
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.10.038
article 2014
Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.12.049