Sakhila K. Banu

No ORCID on file · 37 papers in corpus · active 2007-2025

Study types

  • article 25
  • dataset 8
  • other 2
  • letter 1
  • review 1

Condition tags

  • endometriosis 28
  • mesh:D004715 13
  • infertility 7
  • chronic_pelvic_pain 4
  • mesh:D017699 1
letter 2025
New perspectives about the article “Dual inhibition of AKT and ERK1/2 pathways restores the expression of progesterone Receptor-B in endometriotic lesions through epigenetic mechanisms"
·doi:10.1016/j.mce.2025.112496
other 2024
Dual inhibition of AKT and ERK1/2 pathways restores the expression of progesterone Receptor-B in endometriotic lesions through epigenetic mechanisms
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2024.112290

Endometriosis is an estrogen-dependent and progesterone-resistant gynecological inflammatory disease of reproductive-age women. Progesterone resistance, loss of progesterone receptor -B (PR-B) in the stromal cells of the endometrium, is one…

review 2023
Endocrine disruptors and endometriosis
Reproductive toxicology (Elmsford, N.Y.) ·doi:10.1016/j.reprotox.2022.11.007

Endometriosis is a hormone-dependent inflammatory gynecological disease of reproductive-age women. It is clinically and pathologically characterized by the presence of functional endometrium as heterogeneous lesions outside the uterine cavi…

article 2022
Effects of selective inhibition of prostaglandin E2 receptors EP2 and EP4 on the miRNA profile in endometriosis
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2022.111728
article 2021
Effects of dual inhibition of AKT and ERK1/2 pathways on endometrial pro-inflammatory, hormonal, and epigenetic microenvironment in endometriosis
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2021.111446
article 2018
Dual inhibition of ERK1/2 and AKT pathways is required to suppress the growth and survival of endometriotic cells and lesions
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2018.12.011
article 2018
Molecular, Cellular, and Epigenetic Signatures of Prostaglandin E2 in Endometriosis
·doi:10.2174/1573404814666180108144810

Background: Endometriosis is a debilitating and chronic inflammatory gynecological disease of reproductive age women. Two major clinical symptoms of endometriosis are chronic pelvic pain and infertility, which profoundly affect the quality …

article 2016
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms

Short Title: PGE2 signaling in adhesion of human endometriotic cells Summary Sentence: Selective inhibition of PGE2 receptors EP2 and EP4 disassembled integrin linkage mechanisms and disturbed integrin outside-in and inside-out signaling pa…

article 2016
Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Inhibits Adhesion of Human Endometriotic Epithelial and Stromal Cells

Endometriosis is a chronic gynecological disease of reproduc-tive age women characterized by the presence of functional endometrial tissues outside the uterine cavity. Interactions between the endometriotic cells and the peritoneal extracel…

article 2015
Molecular and preclinical basis to inhibit PGE 2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1507931112

Endometriosis is a debilitating, estrogen-dependent, progesterone-resistant, inflammatory gynecological disease of reproductive age women. Two major clinical symptoms of endometriosis are chronic intolerable pelvic pain and subfertility or …

article 2015
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 modulates DNA methylation and histone modification machinery proteins in human endometriotic cells
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2015.03.023
article 2013
PPARγ Activation Inhibits Growth and Survival of Human Endometriotic Cells by Suppressing Estrogen Biosynthesis and PGE2 Signaling.
Endocrinology ·doi:10.1210/en.2013-1168

Endometriosis is a chronic inflammatory disease of reproductive age women leading to chronic pelvic pain and infertility. Current antiestrogen therapies are temporizing measures, and endometriosis often recurs. Potential nonestrogenic or no…

article 2013
Unraveling the moleculr interactions between PGE2 signaling and pain pathways in endometriosis
·doi:10.1016/j.fertnstert.2013.07.1701
dataset 2012
Faculty Opinions recommendation of A polymorphism in a let-7 microRNA binding site of KRAS in women with endometriosis.
·doi:10.3410/f.14267150.15779305
dataset 2012
Faculty Opinions recommendation of Sprouted innervation into uterine transplants contributes to the development of hyperalgesia in a rat model of endometriosis.
·doi:10.3410/f.714597893.793462570
article 2012
Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Inhibits Adhesion of Human Endometriotic Epithelial and Stromal Cells Through Deregulated Integrin-Mediated Mechanisms.
·doi:10.1093/biolreprod/87.s1.545

BACKGROUND: Endometriosis is a chronic inflammatory disease of reproductive-age women. Adhesion of endometriotic epithelial and stromal cells to peritoneum is mediated through integrin and extracellular matrix (ECM) protein interactions. In…

article 2012
Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Inhibits Adhesion of Human Endometriotic Epithelial and Stromal Cells Through Suppression of Integrin-Mediated Mechanisms1
Biology of reproduction ·doi:10.1095/biolreprod.112.100883

Endometriosis is a chronic gynecological disease of reproductive age women characterized by the presence of functional endometrial tissues outside the uterine cavity. Interactions between the endometriotic cells and the peritoneal extracell…

article 2012
Selective Inhibition of Prostaglandin E2 Receptors EP2 and EP4 Inhibits Growth of Experimental Endometriosis in Nude Mice Evaluated by Real-time Noninvasive Imaging and Fluorescence Microscopy.
·doi:10.1093/biolreprod/87.s1.550

Endometriosis is a highly prevalent estrogen-dependent gynecological inflammatory disease of reproductive-age women characterized by the presence of functional endometrial cells outside the uterus commonly leading to inflammation, pain and …

dataset 2011
Faculty Opinions recommendation of Experimental endometriosis in immunocompromised mice after adoptive transfer of human leukocytes.
·doi:10.3410/f.1162825.11112056
dataset 2011
Faculty Opinions recommendation of Prostaglandin E2: the master of endometriosis?
·doi:10.3410/f.13109957.14433055
article 2010
Expression and Regulation of Prostaglandin Biosynthetic Enzymes Cox-2 and Pges-1 and Receptors EP1, EP2, EP3, and EP4 in Endometriosis in the Nonhuman Primate.
·doi:10.1093/biolreprod/83.s1.168

Endometriosis is a debilitating disease where endometrium-like tissue forms lesions outside the uterus that result in chronic pelvic pain and infertility in 10-20% of women of reproductive age. Endometriosis is an estrogen-dependent disease…

dataset 2010
Faculty Opinions recommendation of A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model.
·doi:10.3410/f.7014956.7223054
dataset 2010
Faculty Opinions recommendation of Inhibition of CD36-dependent phagocytosis by prostaglandin E2 contributes to the development of endometriosis.
·doi:10.3410/f.1582957.2501057
dataset 2010
Faculty Opinions recommendation of Prostaglandin E2 via steroidogenic factor-1 coordinately regulates transcription of steroidogenic genes necessary for estrogen synthesis in endometriosis.
·doi:10.3410/f.5294956.5238054
dataset 2010
Faculty Opinions recommendation of The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis.
·doi:10.3410/f.3541956.3241054