G. Mage

Our recent DNA microarray analysis using tissue obtained by laser capture microdissection (LCM) identified up-regulation of RON (a tyrosine kinase receptor) during the late secretory phase in eutopic endometrial epithelial cells from patien…

OBJECTIVE: To identify any relationship between cyclooxygenase-2 expression and the intensity of severe, endometriosis-related dysmenorrhea. DESIGN: Prospective study. SETTING: University hospital. PATIENT(S): Patients with deep endometr…

Endometriosis, a common gynecological disorder that causes infertility and pelvic pain, is defined as the presence of endometrial glands and stroma within extra-uterine sites. However, despite extensive studies its etiology and pathogenesis…

OBJECTIVE: To quantify the expression of transforming growth factor beta1 in nerve fibers in endometriotic lesions and to correlate it with dysmenorrhea and appearance of endometriotic implants. DESIGN: Prospective comparative study. SETT…

The laparoscopic management of ovarian endometrioma was reported more than 15 years ago. An anonymous survey conducted among gynaecologists in the UK showed that 50% of ovarian endometrioma are still managed by laparotomy. This surprising r…

Objective To review and to discuss the current approaches which may be proposed to prevent adhesions in the surgical management of pelvic endometriosis. Methods The current literature was reviewed using a Medline search and data from the Co…

Three surgical units were involved in a prospective comparative study: the Pavillon Paul Gellé in Roubaix, France for vaginal hysterectomies; the Hôtel Dieu Polyclinic in Clermont-Ferrand, France for total percoelioscopic hysterectomies; an…

BACKGROUND: Ovarian response during IVF cycles after laparoscopic ovarian cystectomy for endometriotic cysts >3 cm is controversial. A retrospective study was designed to study this problem. METHODS: At laparoscopy, endometriomas >3 cm wer…

Colo-rectal endometriosis requiring colon resection are reported in 8 patients to illustrated the diagnostic and therapeutic problems encountered in the management of this uncommon localisation. Pericatamenial or catamenial bowel symptoms a…

Using technological progress, laparoscopic lymphadenectomy is becoming the standard for staging of pelvic cancer. In the same way more extensive procedures such as para-aortic lymph nodes dissection and radical hysterectomy have been demons…

From their experience and from data in the literature, the authors try to define the respective place of the different treatments for endometriosis, especially those of operative laparoscopy. In cases of endometriosis-associated infertility…

From January 1989 to December 1990, 196 patients were treated by hysteroscopic endometrial resection for abnormal uterine bleeding. A survey in February 1993 revealed a satisfaction rate of 82%. Persistence of abnormal bleeding after resect…

OBJECTIVE: Study of factors affecting risk of failure after hysteroscopic endometrial resection. METHODOLOGY: A retrospective study of 196 patients treated by hysteroscopic endometrial resection for abnormal uterine bleeding from January 1…

A perfect endometriosis classification should be a common language and an expert system which helps the gynaecologist to decide the treatment of each patient. The staging of endometriosis is not a new idea; the first classification based on…

Thirty-three patients were selected for laparoscopic hysterectomy and operated on in the Department of Obstetrics, Gynecology and Reproductive Medicine of Clermont-Ferrand University Hospital. Surgical techniques included blunt dissection w…

Studying the incidence of bilateral adnexal disease and dense adhesions, two groups of patients with severe endometriosis were distinguished, suggesting that a stage V needs to be considered in the AFS classification.

Laparoscopic hysterectomy is a recent procedure. We present our preliminary results about 44 patients. In 77.3% of cases (34 patients) the operation was carried out completely by laparoscopy and 10 patients (22.7%) required conversion of th…

Forty-two patients who underwent a second-look laparoscopy after a unilateral or bilateral intraperitoneal cystectomy for treatment of an ovarian endometrioma of greater than 3 cm were included. At second-look laparoscopy, 92.4% of the adne…

Benign ovarian cysts can be diagnosed and treated by surgical laparoscopy which, like laparotomy, permits a histological examination. Ovarian cysts that are, or are suspected of being malignant must be removed by laparotomy after evaluation…

The last ten years have been characterized by a tremendous change in laparoscopy. Initially used exclusively for diagnosis, laparoscopy is now a surgical method in its own right and plays a strategic role. Long-term evaluation of results fo…