OBJECTIVE: With a prospective study, to evaluate the existence of two distinct clinical diseases in the endometriosis syndrome, by comparing pain symptoms and quality of life from patients with minimal endometriosis (AFS-R<5) and data from …
The minimum distance between the vaginal mucosal epithelium and the endometriotic glands was <1,000 microm in 30 patients (49.2%), <2,000 microm in 44 patients (72.1%), and <5,000 microm in 60 patients (98.4%). Our findings provided histolo…
Journal de Gynecologie Obstetrique et Biologie de la Reproduction - Vol. 36 - N° 2 - p. 151-161
BACKGROUND: Deep infiltrating endometriosis (DIE) is commonly associated with severe pain. The pain can be managed successfully with GnRH agonists or continuous progestins. The precise molecular mechanism by which DIE causes pain or why hor…
L’endométriose est une maladie bénigne, très invalidante et fréquente, définie par la présence d’endomètre, épithélium et stroma, en situation ectopique. Sa physiopathologie, et celle des douleurs qui l’accompagnent, est mal connue. Les sig…
Resume ´ : L'endometriose est une maladie benigne, tres invalidante et frequente, definie par la presence d'endo- metre, epithelium et stroma, en situation ectopique. Sa physiopathologie, et celle des douleurs qui l'accompa- gnent, est mal …
From the literature, the crucial knowledge were drawn among endometriosis related infertility. Endometriosis is an important factor of infertility in minimal or light stages and a major one in mild or moderate stages. Thus, a laparoscopy mu…
Although malignant degeneration of cutaneous endometriosis is rare at only 0.3-1% in endometriosis surgical scars, diagnosis and management need to be defined. A case of malignant degeneration of perineal endometriosis is reported, with a r…
OBJECTIVE: To investigate whether genes that had been found to be differentially expressed in deep-infiltrating endometriosis and matched eutopic endometrium in our previous complementary DNA microarray study also are differentially express…
Endometriosis has long been considered as a disease of women over 30 years old. However, recent data from the literature demonstrated its high incidence in teenagers. Endometriosis in teenagers is generally associated with chronic pelvic pa…
OBJECTIVE: To investigate whether WT1 protein expression is altered in eutopic endometrium of endometriosis patients. DESIGN: Prospective study. SETTING: University hospital. PATIENT(S): Patients with endometriosis and fertile women with…
OBJECTIVE: Evaluation of fertiloscopy's place in the management of female infertility. PATIENTS AND METHODS: Retrospective study including 229 women presenting primary or secondary infertility without pathology raising of an evident surgic…
We investigated relationships between delay of surgical diagnosis and severity of disease in 95 patients with symptomatic deep infiltrating endometriosis. The delay before surgical diagnosis of deep infiltrating endometriosis was significan…
OBJECTIVE: To investigate differentially expressed genes in epithelial and stromal cells of eutopic endometrium from patients with deep endometriosis and women with normal pelvic cavities using laser capture microdissection and complementar…