Endometrial changes associated with myomata of the uterus

Deligdish L, L Deligdish, Loewenthal M, M Loewenthal
Journal of clinical pathology · 1970 · vol. 23(8) , pp. 676–680 · doi:10.1136/jcp.23.8.676 · PMID:5488038 · PMC476867 · W1989803373
Other OA: bronze CC0 ⤵ 17 in-corpus citations
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Endometrial tissue from uteri with myomata showed glandular atrophy, hyperplasia, and distortion, with adenomyosis also observed, suggesting histological diagnostic markers for uterine myomata.

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Abstract

The endometrium of 30 uteruses with myomata was studied at four standard sites. Glandular atrophy over a myoma or opposite a myoma was the most constant finding. At the margin of a myoma hyperplastic glands were frequently found, and distorted, elongated, or dilated glands were present at this site in half of all specimens. Other changes included adenomyosis and the separation of glands by muscle fibres from the basal layer of the endometrium. The coexistence of many of these findings in endometrial curettings can lead to the histological diagnosis of uterine myomata. Two factors, mechanical and hormonal, may be responsible and their mechanisms are discussed.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometrium Leiomyoma Uterine Neoplasms Adult Adult Atrophy Atrophy Atrophy Endometriosis Endometriosis Endometriosis Endometrium Endometrium Female Female Humans Humans Hyperplasia Hyperplasia Hyperplasia

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (9)

Cited by (16)

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