Comparison of Endometrial Changes in Uterine Leiomyoma and Adenomyosis of Uterus with Correlation of Serum Estradiol and Progesterone Levels

In: Journal of Medical Science And clinical Research · 2017 · vol. 5(11) · doi:10.18535/jmscr/v5i11.82 · W2768749076
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This study examined endometrial changes in uterine leiomyoma and adenomyosis and their correlation with serum estradiol and progesterone levels.

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Abstract

Background: Both leiomyoma and adenomyosis are commonly encountered gynecological pathologies. It is a well-established fact that hyperestrogenic state is associated with growth of leiomyoma but the exact etiology of adenomyosis is unknown. Adenomyosis is also thought to be an estrogen dependent disease. Similarly, it has also been found that progesterone receptors are increased in leiomyomas whereasa decreased responsiveness of the ectopic endometrium to progesterone has been found in adenomyosis. Thus these two hormones are intricately related to leiomyoma and adenomyosis. Aims: The aim of this study is to note the changes in endometrium that can be found in the respective cases of uterine leiomyoma and adenomyosis of uterus.

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adenomyosis

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