Datenlage zur Endometriose

In: Der Gynäkologe · 2007 · vol. 40(7) , pp. 521–526 · doi:10.1007/s00129-007-2015-6 · W1573864060
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Endometriosis, a complex disease affecting many women, is infrequently diagnosed, with an average 7-year delay from symptom onset to diagnosis, highlighting a need for increased physician awareness.

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This paper reviews the available evidence on endometriosis diagnostics, emphasizing that definitive diagnosis requires operative assessment because imaging cannot reliably detect small lesions. It discusses the role of additional endoscopic examinations such as rectosigmoidoscopy or cystoscopy as being appropriate only when specific symptoms are present (e.g., cyclic recurrent hematuria). The authors report that, despite endometriosis being the second most common reproductive-age disease in women, the literature remains highly heterogeneous and shows underdiagnosis with an average delay of about 7 years from symptom onset to correct diagnosis. This paper is centrally about endometriosis — it summarizes the state of evidence for diagnosis, diagnostic delay, and limitations of imaging and endoscopic tests.

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Zusammenfassung Die Endometriose ist eine sehr komplexe Erkrankung, und die Symptome sind sehr unterschiedlich. Eine definitive Diagnose kann nur über einen operativen Eingriff gestellt werden, denn bildgebende Verfahren können kleinere Läsionen nicht ausreichend sicher darstellen. Endoskopische Zusatzuntersuchungen wie z. B. die Rektosigmoidoskopie oder Zystoskopie sind nur indiziert beim Vorliegen konkreter Symptome, z. B. zyklisch rezidivierende Hämaturie. Die Endometriose ist die zweithäufigste Erkrankung der Frau im reproduktionsfähigen Alter. Trotz dieser Häufigkeit sind die vorhandenen Daten in der Literatur sehr inhomogen. Die vorhandenen Daten zeigen, dass die Endometriose viel zu selten diagnostiziert wird und vom Auftreten der ersten Symptome bis zur korrekten Diagnosestellung etwa 7 Jahre vergehen. Allein diese Tatsache belegt, dass die Symptome und die Beschwerden der Endometriose mehr in das Bewusstsein der behandelnden Ärzte rücken muss, damit die Endometriose nicht mehr als „Krankheit ohne Lobby“ bezeichnet wird. Abstract Endometriosis is a very complex disease with highly variable symptoms. A definitive diagnosis can only be made operatively as imaging techniques cannot clearly distinguish small lesions. Additional endoscopic examination such as rectosigmoidoscopy or cytoscopy are only indicated when concrete symptoms are present, e.g. by cyclically recurrent hematuria. Endometriosis is the second most common disease in women of reproductive age. Nevertheless, the data in the literature are very heterogeneous. These show that endometriosis is diagnosed too infrequently and that the time from the beginning of symptoms to a correct diagnosis lasts about 7 years. All of these facts show that the symptoms and complaints must move more into the consciousness of the physician so that endometriosis can no longer be referred to as the “disease without a lobby”. Similar content being viewed by others Literatur Schweppe KW (2003) Endometriose: Was tun – und wann? Frühe Diagnose, bessere Differentialdiagnose und individuelle Behandlung. Frauenarzt 44: 739–744 Schweppe KW (2003) Endometriose – Eine Erkrankung ohne Lobby. Zentralbl Gynakol 125: 233 Pritts EA, Taylor RN (2003) An evidence-based evaluation of endometriosis-associated infertility. Endocrinol Metab Clin North Am 32: 653–667 Rokitansky K von (1860) Über Uterusdrüsen-Neubildung in Uterus und Ovarialsarkomen. Z Ges Ärzte Wien 37: 577–593 American Society for Reproductive Medicine (1997) Revised American society for Reproductive Medicine classification of endometriosis. Fertil Steril 67: 817–822 Tuttlies F, Keckstein J, Ulrich U et al. (2005) Enzian-score. 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Clin Exp Obstet Gynecol 21: 195–197 Waller KG, Lindsay P, Curtis P, Shaw RW (1993) The prevalence of endometriosis in women with infertile partners. Eur J Obstet Gynecol Reprod Biol 48: 135–139 Kashima K, Ishimaru T, Okamura H et al. (2004) Familial risk among Japanese patients with endometriosis. Int J Gynecol Obstet 84: 61–64 Kuohung W, Jones GL, Vitonis AF et al. (2002) Characteristics of patients with endometriosis in the United States and the United Kingdom. Fertil Steril 78: 767–772 Husby GK, Haugen RS, Moen MH (2003) Diagnostic delay in women with pain and endometriosis. Acta Obstet Gynecol Scand 82: 649–653 Weismann A, Hartz AJ, Hansen MD, Johnson SR (2004) The natural history of primary dysmenorrhea: a longitudinal study. BJOG 111: 345–352 Leibson CL, Good AE, Hass SL et al. (2004) Incidence and characteristics of diagnosed endometriosis in a geographically defined population. Fertil Steril 82: 314–321 Sangi-Haghpeykar H, Poindexter AN (1995) Epidemiology of endometriosis among parous women. Obstet Gynecol 85: 983–992 Hemming R, Rivard M, Olive DL et al. (2004) Evaluation of risk factors associated with endometriosis. Fertil Steril 81: 1513–1521 Interessenkonflikt Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Oehmke, F., Suwandinata, F., Deisting, C. et al. Datenlage zur Endometriose. Gynäkologe 40, 521–526 (2007). https://doi.org/10.1007/s00129-007-2015-6 Published: Issue date: DOI: https://doi.org/10.1007/s00129-007-2015-6

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