Endometriosis and infertility: what do we do for each stage?
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Abstract
Endometriosis and infertility have been linked in the discipline of gynecology for more than a century. There is evidence that endometriosis can and does decrease fertility. However, our ability to determine fertility prognosis based on a staging system is severely limited. Treatment options include medical therapy, surgical intervention, and assisted reproduction. For endometriosis-associated infertility, medical therapy seems to have no value alone. Surgical therapy is beneficial for all stages of diseases, as in assisted reproduction. The relative value of these two latter approaches, however, is untested. Our suggestions for the treatment of early-stage endometriosis are surgery and/or superovulation with intrauterine insemination as first-line treatments. For more advanced disease, with tubal damage, surgery or in vitro fertilization are options. For the most advanced cases, in vitro fertilization preceded by 3 months of medical treatment of the endometriosis is advised.
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Cited by (15)
- Disorders of the Peritoneum 2018
- A Comparison of Treatment Modalities in 69 Patients with Endometriosis and/or Endometrioma and Review of the Literature 2015
- Roles of regulatory T cells in endometriosis-associated infertility 2014
- Prevalence and Polymorphism in Interferon-γ Gene (CA) Repeats with Different Stages of Endometriosis 2013
- Fertility Outcome after Operative Laparoscopy versus No Treatment in Infertile Women with Minimal or Mild Endometriosis. 2012
- Involvement of pelvic inflammation–related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis 2012
- Endometriosis Is Associated with Progesterone Resistance in the Baboon (Papio anubis) Oviduct: Evidence Based on the Localization of Oviductal Glycoprotein 1 (OVGP1)1 2008
- Datenlage zur Endometriose 2007
- Efectos del tratamiento quirúrgico de la endometriosis ovárica sobre los resultados reproductivos en pacientes que realizan tratamientos de fecun- dación "In Vitro" Effects of the surgical treatment of the ovarian endometriosis on the reproduc- tive results in patients that carry out treatment of "In Vitro" fertilization 2006
- HOXA10 expression in ectopic endometrial tissue 2006
- Regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic protein 1 in follicular fluid accumulate differentially in patients with and without endometriosis undergoing in vitro fertilization 2006
- Optimising in vitro fertilisation (IVF) outcome in women with endometriosis 2006
- Laparoscopic management of endometriosis 2006
- Endometriose und Infertilität 2005
- The Link between Exposure to Dioxin and Endometriosis: A Critical Reappraisal of Primate Data 2004
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