Treatment of severe cyclical mastalgia

A C Montgomery, B V Palmer, Subrata Kumar Biswas, S Biswas, J C Monteiro, J C M P Monteiro
Journal of the Royal Society of Medicine · 1979 · vol. 72(7) , pp. 489–491 · doi:10.1177/014107687907200705 · PMID:552546 · PMC1436931 · W8011895
Non-randomised trial OA: bronze CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-13 ⓘ

Bromocryptine and danazol equally relieved severe cyclical mastalgia in 70% of patients, with bromocryptine preferred due to fewer side effects and a significant reduction in prolactin levels.

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Abstract

In a sequential study to compare the efficacy of bromocryptine and danazol in the treatment of severe cyclical mastalgia, 70% of patients in both groups were relieved of their symptoms. Patients tended to prefer bromocryptine because of its limited side effects. There was a significant fall in prolactin levels with bromocryptine, but not with danazol.

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MeSH descriptors

Breast Diseases Bromocriptine Danazol Pregnadienes Adult Breast Diseases Bromocriptine Danazol Female Humans Middle Aged Pain Periodicity Pregnadienes Prolactin Prolactin

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References (14)

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