Endometrial Stem Cells and Endometriosis
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Endometrial stem cells possess high proliferative, differentiation, and angiogenic capabilities, showing potential for tissue engineering and cell therapy applications.
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Abstract
On this basis, endometrial stem cells (EnSCs), characterized by higher abilities for proliferation, differentiation, fast angiogenesis during menstruation and immune tolerance for embryo during pregnancy, have been considered as a valuable source of stem cells (Gargett, Chan et al. 2007; Meng, Ichim et al. 2007). Several researches have demonstrated presence of highly pleuripotent mesenchymal stem cells in endometrium by differentiation potency to various cell types such as, insulin producer cells (Li, Chen et al. 2010), osteoblasts (Ai, Mehrabani. 2010) , odontoblasts (Ai, Tabatabaei et al. 2009), neurons (Wolff, Gao et al. 2011) (Ai, Tabatabaei et al. 2009) and Myoblast (Ai, Tabatabaei et al. 2009). These findings may open up new opportunities to use endometrial stem cells in tissue engineering and cell therapy (Ai , Mehrabani. 2009).
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