Understanding Ultrasound Features that Predict Symptom Severity in Patients with Adenomyosis: a Systematic Review

Hiroshi Kobayashi, Shogo Imanaka
Reproductive sciences (Thousand Oaks, Calif.) · 2023 · vol. 31(2) , pp. 320–331 · doi:10.1007/s43032-023-01318-5 · PMID:37584856 · W4385851681
review OA: closed CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This systematic review summarizes ultrasound features correlating with adenomyosis symptoms, finding that while lesion thickness and diffuse or focal adenomyosis may be associated with symptoms, no consensus exists for predicting severity from ultrasound alone.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This systematic review examined the ultrasound features reported to correlate with the clinical severity of adenomyosis symptoms by searching PubMed and Google Scholar up to March 2022, summarizing how lesion topography and other ultrasound findings have been used to map disease. Ultrasound features were organized into direct signs (ectopic endometrial tissue within the myometrium) and indirect signs (myometrial structural changes and translesional vascularity), with several reports linking lesion thickness, diffuse/internal disease, and focal adenomyosis patterns to dysmenorrhea, abnormal uterine bleeding, and infertility, respectively. However, the review emphasizes that symptom severity–driven treatment decisions are not well predicted by ultrasound criteria, and it reports no current consensus that symptom severity can be reliably predicted from ultrasound features, limiting clinical certainty. This paper is centrally about endometriosis and adenomyosis research within adenomyosis — specifically ultrasound markers and classifications proposed to predict adenomyosis symptom severity.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Infertility Infertility Infertility Infertility Infertility

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References (53)

Cited by (2)

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
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License: CC0 · commercial use OK