A Classification Proposal for Adenomyosis Based on Magnetic Resonance Imaging

Hiroshi Kobayashi, Matsubara S, Sho Matsubara
Gynecologic and obstetric investigation · 2020 · vol. 85(2) , pp. 118–126 · doi:10.1159/000505690 · PMID:32160631 · W3011289356
review OA: closed CC0 ⤵ 42 in-corpus citations
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This review proposes an MRI-based adenomyosis classification system accounting for subtype heterogeneity, lesion pattern, extent, concomitant pathologies, and localization to potentially monitor symptom severity.

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Abstract

There is a lack of an international consensus on adenomyosis classification that is useful for clinical practice and research. This article reviews advancements in the classification of adenomyosis, and the existing limitations. We collected a literature search from PubMed and Embase database up to March 2019. The proposed adenomyosis classification is based on magnetic resonance imaging and clinically relevant parameters. Adenomyosis is not a disease of homogeneity but is composed of multiple heterogeneous subtypes. Adenomyosis represents a spectrum of lesions, ranging from increased thickness of the junctional zone to focal or diffuse lesions involving the entire uterine wall. Potentially important parameters to be included in the classification could be affected area (internal or external adenomyosis), pattern (focal or diffuse), size or volume (myometrial involvement <1/3, 2/3 of uterine wall), concomitant pathologies (none, peritoneal endometriosis, ovarian endometrioma, deep infiltrating endometriosis, uterine fibroids, or others) and localization (anterior, posterior, left lateral, right lateral, or fundal). We propose a simplified classification system to monitor symptom severity against morphological types or extent of adenomyosis using the combination of previously published classifications as a starting point. More studies are needed to investigate whether this classification represents a useful tool for disease assessment in clinical practice and research.

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Condition tags

endometriosisadenomyosisdie_deep_infiltratingendometrioma

MeSH descriptors

Adenomyosis Adenomyosis Magnetic Resonance Imaging Magnetic Resonance Imaging Adenomyosis Adenomyosis Adult Endometriosis Endometriosis Endometriosis Female Humans Leiomyoma Leiomyoma Leiomyoma Myometrium Myometrium Myometrium Peritoneal Diseases Peritoneal Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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License: CC0 · commercial use OK