Peritoneal fluid concentrations of interleukin-11 in women with endometriosis

Gazvani MR, M R Gazvani, M.Rafet Gazvani, Bates M, Michelle Bates, M. Bates, Vince G, Gillian Vince, G Vince, Christmas SE, S Christmas, Stephen E. Christmas, D I Lewis-Jones, D. I. Lewis‐Jones, Charles Kingsland, Lewis-Jones DI, C Kingsland, Kingsland C
Fertility and sterility · 2000 · vol. 74(6) , pp. 1182–1186 · doi:10.1016/s0015-0282(00)01613-7 · PMID:11119747 · W2157921419
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This study measured peritoneal fluid concentrations of interleukin-11 in women with endometriosis to investigate its role in the condition.

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Abstract

OBJECTIVE: To determine the peritoneal fluid concentrations of interleukin-11 (IL-11) in women with endometriosis as compared with the control group. DESIGN: A prospective, controlled study. SETTING: The obstetrics and gynecology department of a teaching hospital and a university immunology department. PATIENT(S): Sixty consecutive women undergoing laparoscopic surgery for benign gynecological indications. INTERVENTION(S): Peritoneal fluid was obtained during laparoscopy, and the concentration of IL-11 was measured. MAIN OUTCOME MEASURE(S): Concentration of IL-11 in correlation with the presence of endometriosis, its stage, and the phase of the menstrual cycle. RESULT(S): IL-11 was detectable in the peritoneal fluid of 64% of women tested. Concentrations of IL-11 showed no correlation with the presence of endometriosis, the American Fertility Society stage of the disease, or the phase of the menstrual cycle. CONCLUSION(S): We found no evidence to suggest that IL-11 is involved in the pathogenesis of pelvic endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Interleukin-11 Adult Adult Ascitic Fluid Ascitic Fluid Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Interleukin-11 Interleukin-11 Menstrual Cycle Menstrual Cycle Osmolar Concentration

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (38)

Cited by (6)

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