Endometriosis.

E J Thomas, Eric J. Thomas, Thomas EJ
BMJ (Clinical research ed.) · 1993 · vol. 306(6871) , pp. 158–159 · doi:10.1136/bmj.306.6871.158 · PMID:8443475 · PMC1676597 · W4242782647
editorial OA: bronze CC0 ⤵ 18 in-corpus citations
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⚙ AI-generated summary by claude@2026-07, 2026-07-09 ⓘ

This paper discusses strategies, like adding an antidote or developing safer derivatives, to prevent deaths from paracetamol overdose, noting current combinations are costly and underutilized.

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Abstract

encourage more people to take an overdose.It should, however, reduce the likelihood of an accidental overdose being taken from severe pain and increase the chance that if a patient's family knows of the overdose they will encourage him or her to seek prompt medical advice.The pharmaceutical industry is in a pivotal position to address the problem of the continuing high mortality from paracetamol overdose as the addition of an antidote, such as methionine, to all available preparations might prevent every death that currently occurs.At present paracetamol- methionine combinations are costly, little publicised, and rarely prescribed.Adding methionine to all preparations of paracetamol might increase prices and therefore reduce sales.Another solution might be to develop non-hepatotoxic derivatives of paracetamol.It will indeed be tragic if the mortality from paracetamol overdose over the next quarter of a century proves to be as high as that of the last.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Pelvic Neoplasms Endometriosis Female Humans Pelvic Neoplasms

Citation neighborhood

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References (14)

Cited by (18)

Source provenance

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