An effective minimally invasive method of treating adenomyosis by interstitial laser photocoagulation with the KTP laser

In: Lasers in Medical Science · 1997 · vol. 12(1) , pp. 69–72 · doi:10.1007/bf02763924 · W2019376019
article OA: closed CC0
Full text JSON View on OpenAlex View at publisher
AI-generated summary by claude@2026-06+body, 2026-06-11

Interstitial laser photocoagulation using a KTP laser effectively treated adenomyosis in six patients, rendering them symptom-free and allowing one pregnancy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-11 · read from full text

This paper studied low-power interstitial laser photocoagulation (ILP) as a minimally invasive treatment for adenomyosis using a KTP-YAG laser with 532 nm light delivered by a 600 µm bare-tipped fiber inserted via a needle microstat into abnormal uterine tissue at 3 cm intervals, with energy (Joules) adjusted by treated tissue volume. Six patients were treated, and all reported becoming symptom free; among two who wished to become pregnant, one achieved pregnancy while the other had tubal blockage. The authors note a key limitation that the evidence is based on a very small, uncontrolled sample and that pregnancy outcomes may be influenced by non-uterine factors. This paper is centrally about endometriosis — it specifically evaluates KTP interstitial laser photocoagulation for adenomyosis symptom relief and fertility outcomes.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 3,383 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

Adenomyosis is a condition which mimics uterine leiomyomas in symptomatology and macroscopic appearance, and for which there is no known cure other than hysterectomy. The success of low-power interstitial laser photocoagulation (ILP) in the treatment of uterine leiomyomas suggested that this might also be effective for the treatment of adenomyosis. The KTP 532 nm component of the KTP-YAG laser was used with a 600µm fibre with a bare tip via a needle microstat. The fibre was inserted into the abnormal tissue at spots 3 cm apart and slowly withdrawn, the object being to coagulate the surrounding blood vessels and adenomyotic tissue. The number of Joules required depended on the volume of tissue treated. Six patients were treated. All became symptom free, and of the two who desired to become pregnant, one succeeded. The other had tubal blockage. It had been shown previously that ILP destroys oestrogen receptors, and it is concluded that this new modality offers an effective means of treating adenomyosis by a minimally invasive method. Similar content being viewed by others

References

Bown SG. Phototherapy of tumours.World J Surg 1983,7:700–9 Chapman R. Low power interstitial photocoagulation of uterine leiomyomas by KTP/YAG laser.Lasers Med Sci 1994,9:37–46 Rokitansky K. On uterine neogenesis.Z Gesellshaft Wien 1860,16:577 Cullen TS.Adenomyoma of the Uterus. Philadelphia: W. B. Saunders, 1908 Sahin AA, Silva EG, Landon G et al. Endometrial tissue in myometrial vessels not associated with menstruation.Int J Gynecol Pathol 1989,8:139–46 Zaloudek C, Norris HJ. Mesenchymal tumours of the uterus. In: Kurman RJ (ed)Blaustein’s Pathology of the Female Genital Tract, 3rd edn. New York: Springer-Verlag, 1987:374 Turunen A, Timonen S, Procope B. On the aetiology of endometriosis.Acta Obstet Gynecol Scand 1961,40:206–22 Yamamoto T, Noguchi T, Tamura T et al. Evidence for estrogen synthesis in adenomyotic tissues.Am J Obstet Gynecol 1993,169:734–8 Tamaya T, Motoyama T, Ohono Y et al. Steroid receptor levels and histology of endometriosis and adenomyosis.Fertil Steril 1979,31:396–400 van der Walt LA, San Filippo JS, Siegel JE, Wittliff JL. Estrogen and progestin receptors in human uterus: reference ranges of clinical conditions.Clin Physiol Biochem 1986,4:217–28 Urabe M, Yamamoto T, Kitawaki J et al. Estrogen biosynthesis in human uterine adenomyosis.Acta Endocrinol (Copenh) 1989,121:259–64 Sheets EE, Tsibris JMC, Cook NI et al. In vitro binding of insulin and epidermal growth factor to human endometrium and endocervix.Am J Obstet Gynecol 1985,153:60–5 Chapman R. Low power interstitial photocoagulation of uterine leiomyomas by KTP/YAG laser: a review of fifty consecutive cases.SPIE Proc Med Applic Lasers II 1994,2327:304–12 Grow DR, Filler RB. Treatment of adenomyosis with long-term GnRH analogues: a case report.Fertil Steril 1991,78:538–9 Masters A, Bown SG. Interstitial laser hyperthermia in the treatment of tumours.Lasers Med Sci 1990,5:129–35 Author information Authors and Affiliations Rights and permissions About this article Cite this article Chapman, R., Chapman, K. An effective minimally invasive method of treating adenomyosis by interstitial laser photocoagulation with the KTP laser. Laser Med Sci 12, 69–72 (1997). https://doi.org/10.1007/BF02763924 Received: Accepted: Issue date: DOI: https://doi.org/10.1007/BF02763924

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

adenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK