{"paper_id":"d67ae938-5cb2-464f-a3cd-214d6b29c462","body_text":"Abstract\nAdenomyosis is a condition which mimics uterine leiomyomas in symptomatology and macroscopic appearance, and for which there is no known cure other than hysterectomy. The success of low-power interstitial laser photocoagulation (ILP) in the treatment of uterine leiomyomas suggested that this might also be effective for the treatment of adenomyosis. The KTP 532 nm component of the KTP-YAG laser was used with a 600µm fibre with a bare tip via a needle microstat. The fibre was inserted into the abnormal tissue at spots 3 cm apart and slowly withdrawn, the object being to coagulate the surrounding blood vessels and adenomyotic tissue. The number of Joules required depended on the volume of tissue treated. Six patients were treated. All became symptom free, and of the two who desired to become pregnant, one succeeded. The other had tubal blockage. It had been shown previously that ILP destroys oestrogen receptors, and it is concluded that this new modality offers an effective means of treating adenomyosis by a minimally invasive method.\nSimilar content being viewed by others\nReferences\nBown SG. Phototherapy of tumours.World J Surg 1983,7:700–9\nChapman R. Low power interstitial photocoagulation of uterine leiomyomas by KTP/YAG laser.Lasers Med Sci 1994,9:37–46\nRokitansky K. On uterine neogenesis.Z Gesellshaft Wien 1860,16:577\nCullen TS.Adenomyoma of the Uterus. Philadelphia: W. B. Saunders, 1908\nSahin AA, Silva EG, Landon G et al. Endometrial tissue in myometrial vessels not associated with menstruation.Int J Gynecol Pathol 1989,8:139–46\nZaloudek C, Norris HJ. Mesenchymal tumours of the uterus. In: Kurman RJ (ed)Blaustein’s Pathology of the Female Genital Tract, 3rd edn. New York: Springer-Verlag, 1987:374\nTurunen A, Timonen S, Procope B. On the aetiology of endometriosis.Acta Obstet Gynecol Scand 1961,40:206–22\nYamamoto T, Noguchi T, Tamura T et al. Evidence for estrogen synthesis in adenomyotic tissues.Am J Obstet Gynecol 1993,169:734–8\nTamaya T, Motoyama T, Ohono Y et al. Steroid receptor levels and histology of endometriosis and adenomyosis.Fertil Steril 1979,31:396–400\nvan der Walt LA, San Filippo JS, Siegel JE, Wittliff JL. Estrogen and progestin receptors in human uterus: reference ranges of clinical conditions.Clin Physiol Biochem 1986,4:217–28\nUrabe M, Yamamoto T, Kitawaki J et al. Estrogen biosynthesis in human uterine adenomyosis.Acta Endocrinol (Copenh) 1989,121:259–64\nSheets EE, Tsibris JMC, Cook NI et al. In vitro binding of insulin and epidermal growth factor to human endometrium and endocervix.Am J Obstet Gynecol 1985,153:60–5\nChapman R. Low power interstitial photocoagulation of uterine leiomyomas by KTP/YAG laser: a review of fifty consecutive cases.SPIE Proc Med Applic Lasers II 1994,2327:304–12\nGrow DR, Filler RB. Treatment of adenomyosis with long-term GnRH analogues: a case report.Fertil Steril 1991,78:538–9\nMasters A, Bown SG. Interstitial laser hyperthermia in the treatment of tumours.Lasers Med Sci 1990,5:129–35\nAuthor information\nAuthors and Affiliations\nRights and permissions\nAbout this article\nCite this article\nChapman, R., Chapman, K. An effective minimally invasive method of treating adenomyosis by interstitial laser photocoagulation with the KTP laser. Laser Med Sci 12, 69–72 (1997). https://doi.org/10.1007/BF02763924\nReceived:\nAccepted:\nIssue date:\nDOI: https://doi.org/10.1007/BF02763924","source_license":"CC0","license_restricted":false}