The second time around: reproductive performance after repetitive versus primary surgery for endometriosis
Observational
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⤵ 47 in-corpus citations
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This study evaluated the reproductive outcomes of women undergoing repeat surgeries for endometriosis compared to those having primary surgery.
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Abstract
After repetitive surgery for recurrent endometriosis, 20 of 89 (22%) women achieved spontaneous pregnancy, compared with 165 of 411 (40%) after first-line procedure (adjusted incidence rate ratio, 0.51; 95% confidence interval, 0.32 to 0.82), and the 12- and 24-month cumulative pregnancy rates were 14% and 26% in the former group compared with 32% and 38% in the latter. Among infertile patients at baseline, 13 of 67 (19%) conceived after reoperation compared with 98 of 290 (34%) after primary surgery (adjusted incidence rate ratio, 0.55; 95% confidence interval, 0.30 to 0.99), and the 12- and 24-month cumulative pregnancy rates were 13% and 22% in the former group and 25% and 30% in the latter.
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Cited by (47)
- Predictive factors for spontaneous conception in women with moderate and severe endometriosis following operative laparoscopy: A cohort study 2025
- Pathophysiology and Clinical Implications of Ovarian Endometriomas 2024
- Presence of endometrioma decreased blastocyst formation rate but not impair Assisted Reproductive Technology (ART) outcome 2023
- Morphokinetic analysis of early human embryonic development and its relationship to endometriosis resection: a retrospective time-lapse study using the KIDScore™ D3 and D5 implantation data algorithm 2023
- What is the impact of endometrioma on IVF/ICSI outcomes in patients with endometriosis: A retrospective study 2022
- Presence of Endometrioma Decreased Blastocyst Formation Rate but Not Impair Assisted Reproductive Technology (ART) outcome 2022
- Effect of the mode of delivery on the risk of endometriosis recurrence: a retrospective cohort study 2022
- Preoperative and perioperative intervention reduces the risk of recurrence of endometriosis in mice caused by either incomplete excision or spillage and dissemination 2021
- COUNCELING PATIENTS WITH ENDOMETRIOSIS 2021
- The roles and functions of macrophages in endometriosis 2021
- Long-term Recurrence of Endometriosis in Women with Subfertility Caused by Endometriosis: A Comparison of the Efficacy of Surgery and Assisted Reproductive Technology as Fertilization Treatment Approaches 2020
- The perioperative period: a critical yet neglected time window for reducing the recurrence risk of endometriosis? 2019
- Fertility Preservation in Women with Endometriosis: It is About Time We Talk About it! 2019
- Perioperative Intervention by β-Blockade and NF-κB Suppression Reduces the Recurrence Risk of Endometriosis in Mice Due to Incomplete Excision 2019
- Use of the Endometriosis Fertility Index to Predict Natural Pregnancy after Endometriosis Surgery: A Single-Center Study 2018
- Recurrent endometriosis and IVF: is it still an enigma? 2018
- To operate or not to operate on women with deep infiltrating endometriosis (DIE) before in vitro fertilization (IVF) 2017
- Which is worse? Comparison of ART outcome between women with primary or recurrent endometriomas 2017
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- Which is worse? A comparison of ART outcome between women with primary or recurrent endometriomas 2017
- Estrogen-progestins and progestins for the management of endometriosis 2016
- The Efficacy of Postoperative Cyclic Oral Contraceptives after Gonadotropin-Releasing Hormone Agonist Therapy to Prevent Endometrioma Recurrence in Adolescents 2016
- Deep infiltrating endometriosis affecting the urinary tract-surgical treatment and fertility outcomes in 2004-2013 2016
- Endometriosis-related infertility: ovarian endometrioma per se is not associated with presentation for infertility 2016
- Fertility preservation in women with endometriosis: for all, for some, for none? 2015
- Exploring the relationship between endometriomas and infertility 2015
- Effect of second-line surgery on in vitro fertilization outcome in infertile women with ovarian endometrioma recurrence after primary conservative surgery for moderate to severe endometriosis 2015
- Surgery for endometriosis-associated infertility: do we exaggerate the magnitude of effect? 2015
- An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile Women 2015
- External validation of the endometriosis fertility index (EFI) for predicting spontaneous pregnancy after surgery: further considerations on its validity 2015
- Second surgery for recurrent endometriomas is more harmful to healthy ovarian tissue and ovarian reserve than first surgery 2015
- Endometriosis and infertility: how and when to treat? 2014
- Ovarijska rezerva prije i nakon operacije endometrioma 2014
- Recurrence of ovarian endometrioma after second-line, conservative, laparoscopic cyst enucleation 2013
- Role of surgery in endometriosis-associated subfertility 2013
- Oral contraceptives in the prevention of endometrioma recurrence: does the different progestins used make a difference? 2013
- Comparisons Between Laparoscopy Only Versus In Vitro Fertilization in Combination With Laparoscopy for Increasing Probability of Pregnancy in Patients with Endometriosis Associated Infertility 2012
- Endometriosis and infertility - a consensus statement from ACCEPT (Australasian CREI Consensus Expert Panel on Trial evidence) 2012
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- Surgical Therapies: Peritoneal Endometriosis Surgery 2011
- Endometriosis of the round ligament of the uterus 2011
- Post-operative endometriosis recurrence: a plea for prevention based on pathogenetic, epidemiological and clinical evidence 2010
- Endometriosis-associated infertility: surgery and IVF, a comprehensive therapeutic approach 2010
- Repeat transvaginal ultrasound-guided aspiration of ovarian endometrioma in infertile women with endometriosis 2010
- The outcomes of repeat surgery for recurrent symptomatic endometriosis 2010
- The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review 2009
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