Endometriosis in a patient with Mayer-Rokitansky-Küster-Hauser syndrome and complete uterine agenesis: evidence to support the theory of coelomic metaplasia

Mok-Lin EY, Evelyn Mok-Lin, Evelyn Y Mok-Lin, Adam Wolfberg, Wolfberg A, Heidi Hollinquist, Hollinquist H, Laufer MR, Marc R. Laufer
Journal of Pediatric and Adolescent Gynecology · 2009 · vol. 23(1) , pp. e35–e37 · doi:10.1016/j.jpag.2009.02.010 · PMID:19589710 · W2166530392
Case report OA: closed CC0 ⤵ 48 in-corpus citations
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This case report describes endometriosis in a patient with Mayer-Rokitansky-Küster-Hauser syndrome and complete uterine agenesis, providing evidence to support the coelomic metaplasia theory of endometriosis origin.

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Abstract

BACKGROUND: There are many hypotheses regarding the pathogenesis of endometriosis. Most theories, including retrograde menstruation, require the existence of a uterine structure and endometrial tissue. We report endometriosis with the absence of a uterus. This finding supports the theory of coelomic metaplasia. CASE: A 20-year-old with Mayer-Rokitansky-Küster-Hauser syndrome presented with increasing pelvic pain and underwent laparoscopy. Uterine, cervical, vaginal, and tubal agenesis was confirmed. Stage I endometriosis was visualized in the posterior cul-de-sac and destroyed. She received medical therapy for 5 years until she represented with pain and underwent another laparoscopy, at which endometriosis was again identified and destroyed. SUMMARY AND CONCLUSION: This case of endometriosis in a patient with complete uterine agenesis supports the theory of coelomic metaplasia.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Uterus Endometriosis Endometriosis Female Female Humans Humans Metaplasia Metaplasia Mullerian Ducts Mullerian Ducts Mullerian Ducts Mullerian Ducts Syndrome Syndrome Uterus Uterus Young Adult

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (9)

Cited by (49)

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