Reproductive Tract Anomalies in Adolescent Endometriosis

In: Endometriosis in Adolescents · 2020 · pp. 247–271 · doi:10.1007/978-3-030-52984-0_11 · W3104881400
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Endometriosis is suspected in adolescents with obstructive genital abnormalities, as it is more frequent and severe in this population.

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This paper reviews congenital female reproductive tract anomalies (including Müllerian anomalies), describing their embryologic basis, typical asymptomatic presentation, and common symptomatic manifestations such as cyclic pelvic pain or primary amenorrhea in adolescents and women. It summarizes diagnostic approaches at a high level, stating that definitive diagnosis is achieved with MRI and 3D ultrasonography, and notes that uterine malformations are associated with renal/urinary tract anomalies in 30–50% of cases with recommended urinary screening. The chapter reports that although endometriosis is not shown to be more frequent overall in patients with reproductive tract anomalies, it is diagnosed in about 40% of cases with obstructive anomalies and appears more severe, with earlier and/or more significant symptoms. This paper is centrally about endometriosis — it focuses on how endometriosis is associated with adolescent obstructive reproductive tract anomalies.

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Abstract

Congenital anomalies of the female reproductive tract, including Müllerian anomalies, occur in up to 5% of women and are due to errors of normal embryologic development. Most anomalies are asymptomatic and are discovered incidentally. When symptomatic, they may present with gynecologic and/or obstetrical complications, most commonly cyclic pelvic pain or primary amenorrhea. Definitive diagnosis is achieved with MRI and 3D ultrasonography. Uterine malformations are associated with renal and urinary tract anomalies in 30–50% of cases, and all women diagnosed with a genital anomaly should also undergo screening for urinary system malformation. Although endometriosis has not been shown to be more frequent in patients with reproductive tract anomalies overall, it is diagnosed in approximately 40% of cases of obstructive anomalies. Thus, endometriosis should be suspected in any adolescent with an obstructive genital abnormality, particularly if they experience cyclic or chronic pelvic pain. Endometriosis tends to be more severe in patients with reproductive tract anomalies than those without, resulting in earlier diagnosis and/or more significant symptoms. Treatment of endometriosis in patients with reproductive tract anomalies may involve surgical removal of active remnant endometrium, along with standard hormonal and analgesic therapies. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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Am J Obstet Gynecol [Internet]. 2018 [cited 2018 Dec 7];218(1):114.e1–114.e12. Available from: https://www.ajog.org/article/S0002-9378(17)31184-5/abstract Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2020 Springer Nature Switzerland AG About this chapter Cite this chapter Wolgemuth, T., Sanfilippo, J. (2020). Reproductive Tract Anomalies in Adolescent Endometriosis. In: Nezhat, C.H. (eds) Endometriosis in Adolescents. Springer, Cham. https://doi.org/10.1007/978-3-030-52984-0_11 Download citation DOI: https://doi.org/10.1007/978-3-030-52984-0_11 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-52983-3 Online ISBN: 978-3-030-52984-0 eBook Packages: MedicineMedicine (R0)

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