Analysis of Gene Expression in the Endocervical Epithelium of Wonnen With Deep Endometriosis

Alexander Kopelman, Manoel J B C Girão, Manoel Joâo Batista Castello Girão, T.C. Bonetti, Tatiana C S Bonetti, Cristina V Carvalho, Cristina Valletta de Carvalho, Ismael Dale Cotrim Guerreiro da Silva, Eduardo Schor
Reproductive sciences (Thousand Oaks, Calif.) · 2016 · vol. 23(9) , pp. 1269–1274 · doi:10.1177/1933719116638179 · PMID:27004801 · W2326508092
article OA: closed CC0 ⤵ 4 in-corpus citations
Limited metadata. Only one source feed has indexed this record so far — no abstract, full text, or open-access copy is available through Endo Lab. The publisher's page (linked below) is the canonical location for the actual content. If you have institutional access, use "Find at my library".
View at publisher → View on OpenAlex View on PubMed
⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This study analyzed gene expression in the endocervical epithelium of women with deep endometriosis and found nine differentially expressed genes, including cell cycle and cytokine genes.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper analyzed gene expression in the endocervical epithelium of women with deep endometriosis compared with healthy controls, using RT2 Profiler PCR Arrays on endocervical epithelial cells from 4 patients and 6 controls. Nine genes were reported as upregulated in deep endometriosis, including five cell cycle–related genes (e.g., CCNB1, CCNG1, CUL1, GTF2H1, PCNA), three immune-related cytokine/chemokine genes (C3, CCL21, CXCL14), and ICAM2 associated with dendritic cell pathways. A major limitation is the small sample size (n=4 deep endometriosis), which the study design implies constrains reproducibility and generalizability. This paper is centrally about endometriosis — it profiles endocervical epithelial gene expression differences in women with deep endometriosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis Gene Expression Uterus Adult Endometriosis Epithelial Cells Epithelial Cells Female Gene Expression Profiling Humans Uterus

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (32)

Cited by (4)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:21:07.355239+00:00
License: CC0 · commercial use OK