Can magnetic resonance imaging at 3.0‐Tesla reliably detect patients with endometriosis? Initial results

Maarten Thomeer, Maarten G Thomeer, A. B. Steensma, Anneke B Steensma, Evert J van Santbrink, Francois E Willemssen, François E.J.A. Willemssen, Piotr A Wielopolski, Myriam G Hunink, M. G. Myriam Hunink, Sandra Spronk, Joop S Laven, Joop S.E. Laven, Gabriël P. Krestin, Gabriel P Krestin
Journal of Obstetrics and Gynaecology Research · 2014 · vol. 40(4) , pp. 1051–1058 · doi:10.1111/jog.12290 · PMID:24428703 · W1540750056
article OA: closed CC0 ⤵ 24 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

An optimized 3.0-Tesla MRI protocol achieved 100% patient-level sensitivity for stages II-IV endometriosis and 100% specificity across all stages.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

AIM: The aim of this study was to determine whether an optimized 3.0-Tesla magnetic resonance imaging (MRI) protocol is sensitive and specific enough to detect patients with endometriosis. MATERIAL AND METHODS: This was a prospective cohort study with consecutive patients. Forty consecutive patients with clinical suspicion of endometriosis underwent 3.0-Tesla MRI, including a T2-weighted high-resolution fast spin echo sequence (spatial resolution=0.75 ×1.2 ×1.5 mm³) and a 3D T1-weighted high-resolution gradient echo sequence (spatial resolution=0.75 ×1.2 × 2.0 mm³). Two radiologists reviewed the dataset with consensus reading. During laparoscopy, which was used as reference standard, all lesions were characterized according to the revised criteria of the American Fertility Society. Patient-level and region-level sensitivities and specificities and lesion-level sensitivities were calculated. RESULTS: Patient-level sensitivity was 42% for stage I (5/12) and 100% for stages II, III and IV (25/25). Patient-level specificity for all stages was 100% (3/3). The region-level sensitivity and specificity was 63% and 97%, respectively. The sensitivity per lesion was 61% (90% for deep lesions, 48% for superficial lesions and 100% for endometriomata). The detection rate of obliteration of the cul-the-sac was 100% (10/10) with no false positive findings. The interreader agreement was substantial to perfect (kappa=1 per patient, 0.65 per lesion and 0.71 for obliteration of the cul-the-sac). CONCLUSIONS: An optimized 3.0-Tesla MRI protocol is accurate in detecting stage II to stage IV endometriosis.

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Peritoneal Diseases Adolescent Adult Cohort Studies Endometriosis Endometriosis Endometriosis Female Humans Imaging, Three-Dimensional Imaging, Three-Dimensional Laparoscopy Magnetic Resonance Imaging Magnetic Resonance Imaging Netherlands Ovarian Diseases Ovarian Diseases Ovarian Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (22)

Cited by (24)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:18:40.923139+00:00
License: CC0 · commercial use OK