Comparison of routine pelvic US and MR imaging in patients with pathologically confirmed endometriosis

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Pelvic MR imaging detected significantly more endometriosis and provided greater detail on its location and sequelae than routine pelvic US when compared to surgical or pathological confirmation.

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This study compared routine pelvic ultrasound (US) and pelvic magnetic resonance (MR) imaging for detecting endometriosis in 83 women with surgically or pathologically confirmed endometriosis, using surgery/pathology as the reference standard and including patients who had US followed by MR within 6 months prior to surgery. US detected endometriosis in 22% of patients, whereas MR detected it in 61%, and MR also identified additional disease sites or sequelae in most patients with a positive US; the paper explicitly notes limitations related to the timing intervals and inclusion/exclusion criteria. It further found that 3.0-T MR detected endometriosis more often than 1.5-T MR (72% vs 49%). This paper is centrally about endometriosis — it evaluates and compares routine pelvic US versus pelvic MR imaging for detection and characterization of surgically confirmed endometriosis.

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Abstract

PurposeTo estimate the benefit of pelvic magnetic resonance (MR) imaging after routine pelvic ultrasound (US) in patients with pathologically or surgically proven endometriosis.MethodsPatients with surgically or pathologically proven endometriosis who had routine pelvic US followed by pelvic MR within 6 months prior to surgery were included. Patients were excluded if they had previously confirmed endometriosis, pregnancy, or surgery > 6 months after MR. The detection rate of endometriosis by pelvic US and MR was compared to the surgical/pathological reference standard.Results83 female patients (mean age 40 ± 9) met inclusion criteria and had surgical/pathological confirmation of endometriosis. The mean time interval between pelvic US and MR was 33 ± 43 days, with 64 ± 69 days between MR examination and surgery. US detected endometriosis in 22% (18/83) of patients compared to 61% (51/83) for MR (p < 0.0001). 51% (33/65) of patients with a negative pelvic US exam had a positive MR. MR identified additional sites or sequela in the majority of patients with a positive US (14/18; 78%), including extraovarian locations [e.g., fallopian tubes 7/18 (39%), uterus 7/18 (39%), uterine ligaments 6/18 (33%), posterior cul de sac 5/18 (28%), pelvic side walls 5/18 (28%), abdominal wall 1/18 (6%)] and sequela [ovarian tethering 5/18 (28%), 6/18 (33%) bowel adhesive disease, posterior cul de sac obliteration 2/18 (11%), hydrosalpinx 2/18 (11%), and hydronephrosis 1/18 (6%)]. 3 T MR detected endometriosis in 33/46 (72%) patients compared to 18/37 (49%) for 1.5 T MR (p = 0.03).ConclusionPelvic MR imaging had a higher detection rate of surgically/pathologically proven endometriosis and provides more information about disease location and sequela compared to routine pelvic US.
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Abstract

Purpose To estimate the benefit of pelvic magnetic resonance (MR) imaging after routine pelvic ultrasound (US) in patients with pathologically or surgically proven endometriosis.

Methods

Patients with surgically or pathologically proven endometriosis who had routine pelvic US followed by pelvic MR within 6 months prior to surgery were included. Patients were excluded if they had previously confirmed endometriosis, pregnancy, or surgery > 6 months after MR. The detection rate of endometriosis by pelvic US and MR was compared to the surgical/pathological reference standard.

Results

83 female patients (mean age 40 ± 9) met inclusion criteria and had surgical/pathological confirmation of endometriosis. The mean time interval between pelvic US and MR was 33 ± 43 days, with 64 ± 69 days between MR examination and surgery. US detected endometriosis in 22% (18/83) of patients compared to 61% (51/83) for MR (p < 0.0001). 51% (33/65) of patients with a negative pelvic US exam had a positive MR. MR identified additional sites or sequela in the majority of patients with a positive US (14/18; 78%), including extraovarian locations [e.g., fallopian tubes 7/18 (39%), uterus 7/18 (39%), uterine ligaments 6/18 (33%), posterior cul de sac 5/18 (28%), pelvic side walls 5/18 (28%), abdominal wall 1/18 (6%)] and sequela [ovarian tethering 5/18 (28%), 6/18 (33%) bowel adhesive disease, posterior cul de sac obliteration 2/18 (11%), hydrosalpinx 2/18 (11%), and hydronephrosis 1/18 (6%)]. 3 T MR detected endometriosis in 33/46 (72%) patients compared to 18/37 (49%) for 1.5 T MR (p = 0.03).

Conclusion

Pelvic MR imaging had a higher detection rate of surgically/pathologically proven endometriosis and provides more information about disease location and sequela compared to routine pelvic US. Similar content being viewed by others

References

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Rights and permissions About this article Cite this article Bartlett, D.J., Burkett, B.J., Burnett, T.L. et al. Comparison of routine pelvic US and MR imaging in patients with pathologically confirmed endometriosis. Abdom Radiol 45, 1670–1679 (2020). https://doi.org/10.1007/s00261-019-02124-x Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00261-019-02124-x

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Adult Female Humans Magnetic Resonance Imaging Middle Aged Pelvis Pelvis Sensitivity and Specificity Ultrasonography

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