Ethanol sclerotherapy of ovarian endometrioma: a safe and effective minimal invasive procedure. Preliminary results

Amparo García-Tejedor, Amparo García‐Tejedor, Marta Castellarnau, Jordi Ponce, Ma Eulalia Fernández, MaEulalia Fernández, Maria-Eulalia Fernández-Montolí, Burdio F, Fernando Burdı́o, Fernando Burdio
European journal of obstetrics, gynecology, and reproductive biology · 2015 · vol. 187 , pp. 25–29 · doi:10.1016/j.ejogrb.2015.02.004 · PMID:25739052 · W2041146984
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Ultrasound-guided aspiration with ethanol sclerotherapy was found to be a safe and effective minimal invasive treatment for ovarian endometriomas, with a 12% recurrence rate and minor complications observed.

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Abstract

OBJECTIVE: To study if ultrasound-guided aspiration with ethanol sclerosis is a safe and effective treatment for endometriomas. STUDY DESIGN: We conducted a prospective study of 25 women with 27 endometriomas (two bilateral) measuring 4-10cm in diameter with no suspected malignancy, who underwent ultrasound-guided aspiration and ethanol sclerosis between August 2010 and July 2014. Patients were followed up by ultrasound at 6, 12, 24, and 36 months to identify rates of complication and recurrence. Clinical characteristics of the patients (age, history of infertility, previous surgery, and abdominal pain), the cysts (location, diameter, and volume) and the procedure (duration and complications) were recorded. Kaplan-Meier survival curves were used to analyze the recurrence rates by SPSS statistical software. RESULTS: The recurrence rate after sclerosis was 12%. The mean length of follow-up was 17 (SD 9.9) months. Although no major procedure-related complications were recorded, minor complications included three cases of low abdominal pain during the procedure (10.7%) and two cases of abdominal ethanol extravasation (7.1%). CONCLUSION: Ultrasound-guided aspiration and ethanol sclerotherapy are a safe and effective treatment for endometriomas measuring 4-10cm in diameter with no evidence of malignancy. This conservative treatment could possibly achieve a symptomatic cure while preserving healthy ovarian tissue, thereby improving fertility outcomes and avoiding early menopause.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Ethanol Ethanol Ovarian Diseases Sclerotherapy Adult Adult Endometriosis Endometriosis Endometriosis Female Female Fertility Fertility Humans Humans Middle Aged Middle Aged Ovarian Diseases Ovarian Diseases

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