Successful Pregnancy Following the Ethanol Sclerotherapy in a Woman With Endometrioma With a History of Recurrent Cleavage Formation after ICSI: A Case Report

Saghar Salehpour, Parisa Taherzadeh Borujeni, Nazanin Hajizadeh
In: International Journal of Women's Health and Reproduction Sciences · 2024 · vol. 12(3) , pp. 147–149 · doi:10.15296/ijwhr.2024.8257 · W4401428640
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This case report describes a successful pregnancy achieved via embryo transfer following ethanol sclerotherapy treatment for an endometrioma in a patient with a history of recurrent implantation failure after ICSI.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This case report describes a 30-year-old infertile woman with an endometrioma who had a history of abdominal pain and three cleavage-stage arrest events after ICSI. The authors selected ethanol sclerotherapy (EST) and then initiated ovarian stimulation eight weeks later using a minimal stimulation IVF protocol, retrieving six oocytes and creating three embryos (frozen), with pregnancy achieved after two frozen embryo transfers. The reported caveat is that this is a single-patient case, so conclusions about effectiveness cannot be generalized. This paper is centrally about endometriosis—specifically, use of ethanol sclerotherapy in a patient with an endometrioma to achieve successful pregnancy after prior ICSI failure with cleavage formation arrests.

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Abstract

Introduction: Endometriosis is a chronic inflammatory condition affecting 6 to 10% of the women at reproductive age. The clinical manifestations of this condition differ according to its location. Case Presentation: In this study, the case of a 30-year-old infertile woman presented with a history of abdominal pain and three times cleavage formation arrests after Intracytoplasmic sperm injection (ICSI) was reported. Ethanol sclerotherapy (EST) was selected due to abdominal pain and previous in vitro fertilization (IVF) cycles, and ovarian stimulation was initiated eight weeks later. The patient was stimulated in a minimal stimulation protocol. A total of six oocytes were retrieved, resulting in 3 embryos of good to moderate quality that were frozen. The patient became pregnant following two embryo transfers in the FET cycle. Conclusion: EST may have been considered as a first-line therapy to treat infertility after the failure of IVF. It was found that EST may have improved IVF outcomes.

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Condition tags

endometriosisendometriomainfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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