WITHDRAWN: Integrative Approach Unveils the Therapeutic Potential of Bu-shen-huo-xue recipe in Endometriosis: Insights from Comprehensive Machine Learning, Network Pharmacology, and Single-Cell Analysis

Yibo Chen; Fan Xing; Yang Li; Juan Cui; Yisong Chen

doi:10.1016/j.heliyon.2024.e38889

WITHDRAWN: Integrative Approach Unveils the Therapeutic Potential of Bu-shen-huo-xue recipe in Endometriosis: Insights from Comprehensive Machine Learning, Network Pharmacology, and Single-Cell Analysis

Yibo Chen, Fan Xing, Yang Li, Juan Cui, Yisong Chen

In: Heliyon · 2024 · pp. e38889 · doi:10.1016/j.heliyon.2024.e38889 · W4403118775

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study explored the therapeutic potential of the Bu-shen-huo-xue recipe in endometriosis using machine learning, network pharmacology, and single-cell analysis.

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Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (46)

ACOG Committee Opinion No. 760 Summary: Dysmenorrhea and Endometriosis in the Adolescent via openalex
Chemokine CCL2 enhances survival and invasiveness of endometrial stromal cells in an autocrine manner by activating Akt and MAPK/Erk1/2 signal pathway via openalex
Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis via openalex
Diagnosis and management of endometriosis via openalex
Differential Levels of Regulatory T Cells and T-Helper-17 Cells in Women With Early and Advanced Endometriosis via openalex
Effects of Ulipristal Acetate on Reactive Oxygen Species and Proinflammatory Cytokine Release by Epithelial and Stromal Cells from Human Endometrium and Endometriosis via openalex
Endometriosis via openalex
Endometriosis-Associated Ovarian Carcinomas: How PI3K/AKT/mTOR Pathway Affects Their Pathogenesis via openalex
Epigenetic Dysregulation in Endometriosis: Implications for Pathophysiology and Therapeutics via openalex
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis via openalex
Genomic evidence of Y chromosome microchimerism in the endometrium during endometriosis and in cases of infertility via openalex
Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator via openalex
Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1 via openalex
Knockdown of long noncoding RNA CCDC144NL-AS1 attenuates migration and invasion phenotypes in endometrial stromal cells from endometriosis† via openalex
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis via openalex
Pathogenesis Based Diagnosis and Treatment of Endometriosis via openalex
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review via openalex
Rethinking mechanisms, diagnosis and management of endometriosis via openalex
The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal endometriosis via openalex
Transcriptional profiling of endometriosis tissues identifies genes related to organogenesis defects via openalex
Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis via openalex
Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids via openalex
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[1] ACOG Committee Opinion No. 760 Summary: Dysmenorrhea and Endometriosis in the Adolescent via openalex

[2] Chemokine CCL2 enhances survival and invasiveness of endometrial stromal cells in an autocrine manner by activating Akt and MAPK/Erk1/2 signal pathway via openalex

[3] Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis via openalex

[4] Diagnosis and management of endometriosis via openalex

[5] Differential Levels of Regulatory T Cells and T-Helper-17 Cells in Women With Early and Advanced Endometriosis via openalex

[6] Effects of Ulipristal Acetate on Reactive Oxygen Species and Proinflammatory Cytokine Release by Epithelial and Stromal Cells from Human Endometrium and Endometriosis via openalex

[7] Endometriosis via openalex

[8] Endometriosis-Associated Ovarian Carcinomas: How PI3K/AKT/mTOR Pathway Affects Their Pathogenesis via openalex

[9] Epigenetic Dysregulation in Endometriosis: Implications for Pathophysiology and Therapeutics via openalex

[10] Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis via openalex

[11] Genomic evidence of Y chromosome microchimerism in the endometrium during endometriosis and in cases of infertility via openalex

[12] Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator via openalex

[13] Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1 via openalex

[14] Knockdown of long noncoding RNA CCDC144NL-AS1 attenuates migration and invasion phenotypes in endometrial stromal cells from endometriosis† via openalex

[15] Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis via openalex

[16] Pathogenesis Based Diagnosis and Treatment of Endometriosis via openalex

[17] Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review via openalex

[18] Rethinking mechanisms, diagnosis and management of endometriosis via openalex

[19] The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal endometriosis via openalex

[20] Transcriptional profiling of endometriosis tissues identifies genes related to organogenesis defects via openalex

[21] Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis via openalex

[22] Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids via openalex

[23] W3135648735 via openalex

[24] W3202177173 via openalex

[25] W2008209953 via openalex

[26] W2006617902 via openalex

[27] W4307432965 via openalex

[28] W4309508903 via openalex

[29] W1985969236 via openalex

[30] W4377205868 via openalex

[31] W1982509613 via openalex

[32] W1977267072 via openalex

[33] W1966327575 via openalex

[34] W4393097870 via openalex

[35] W6846406725 via openalex

[36] W6852794353 via openalex

[37] W2159707944 via openalex

[38] W6862421946 via openalex

[39] W2169353806 via openalex

[40] W2489788488 via openalex

[41] W2747877289 via openalex

[42] W2800733044 via openalex

[43] W2092324058 via openalex

[44] W3016136518 via openalex

[45] W3132661792 via openalex

[46] W3134885188 via openalex