Adrenal function during chronic danazol administration
Non-randomised trial
OA: closed
CC0
⤵ 9 in-corpus citations
AI-generated summary
This paper investigated adrenal function in individuals undergoing chronic treatment with danazol, a synthetic androgen.
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Abstract
Ten healthy female volunteers received Danazol, 400 mg twice daily for 90 days. Adrenal function testing then showed a normal capacity of the gland to respond to stimulation with synthetic adrenocorticotrophic hormone, and a lack of suppression of central areas controlling adrenal function by a normal response to the metyrapone challenge.
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References (8)
- Clinical studies with an antigonadotropin-Danazol via openalex
- Influence of Danazol (100 mg) on conception and contraception via openalex
- Pituitary gonadotropin inhibitory activity of danazol via openalex
- The treatment of endometriosis with Danazol via openalex
- doi:10.1152/physrev.1945.25.2.203 via openalex
- W2992693336 via openalex
- doi:10.1016/s0140-6736(65)91526-6 via openalex
- doi:10.1210/jcem-26-10-1116 via openalex
Cited by (9)
- Peripheral androgen levels in danazol-treated premenopausal women 1983
- Danazol 1982
- Review: The mechanism of action of danazol, a novel steroid derivative 1980
- Danazol inhibits human adrenal 21-and 11 beta-hydroxylation in vitro 1980
- Inhibition of adrenal steroidogenesis by danazol in vivo 1980
- Danazol binding to rat androgen, glucocorticoid, progesterone, and estrogen receptors: correlation with biologic activity 1979
- The "treatment" of unexplained infertility with danazol 1979
- The effect of danazol on anterior pituitary function 1977
- Danazol Inhibits Steroidogenesis 1977
Source provenance
- openalex
- last seen: 2026-05-14T06:18:49.133728+00:00
- pubmed
- last seen: 2026-10-08T21:04:05.892929+00:00
- unpaywall
- last seen: 2026-09-17T06:32:46.214484+00:00
License: CC0
· commercial use OK