The pathogenesis of bladder detrusor endometriosis

Paolo Vercellini, Frontino G, Giada Frontino, Anna Pisacreta, Pisacreta A, Olga De Giorgi, Marco Cattaneo, Cattaneo M, Pier Giorgio Crosignani, Crosignani PG
American Journal of Obstetrics and Gynecology · 2002 · vol. 187(3) , pp. 538–542 · doi:10.1067/mob.2002.124286 · PMID:12237623 · W1994332817
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This paper investigates the pathogenesis of endometriosis occurring in the bladder detrusor muscle.

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Abstract

ObjectiveThe purpose of this study was to ascertain whether bladder detrusor endometriosis originates intraperitoneally in the vesicouterine pouch or subperitoneally in the vesicovaginal septum and whether an association exists with uterine adenomyosis.Study designData were collected on clinical, diagnostic, and surgical characteristics of 40 women who were evaluated for primary, histologically confirmed, full-thickness detrusor endometriosis.ResultsIn 19 of the 20 women who underwent surgery, the anterouterine pouch was partially or totally obliterated with the nodule that was located in the posterior wall or dome of the bladder, well above the uterine isthmus, and adherent to the anterior uterine wall or fundus. With one exception, pelvic ultrasonography, cystoscopy, intravenous pyelography, magnetic resonance imaging, and computed tomography identified the lesion cranially with respect to the vesicovaginal septum and excluded uterine adenomyosis.ConclusionVesical endometriosis seems to originate from the implantation of regurgitated endometrial cells in the anterior cul-de-sac and not to be associated with uterine adenomyosis. The metaplasia of subperitoneal mullerian remnants and the uterus-vesical adenomyosis extension theories are not compatible with most imaging, surgical, and pathologic findings.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Urinary Bladder Diseases Adult Endometriosis Endometriosis Endometriosis Female Humans Magnetic Resonance Imaging Tomography, X-Ray Computed Urinary Bladder Diseases Urinary Bladder Diseases Urinary Bladder Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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