Deep endometriosis inflicting the bladder: long-term outcomes of surgical management

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Laparoscopic treatment of bladder endometriosis, including partial cystectomy for full-thickness lesions, was safe and effective, with over 92% of patients asymptomatic or improved long-term.

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This retrospective study assessed the efficacy and safety of laparoscopic surgery for bladder endometriosis, focusing particularly on deep, full-thickness detrusor involvement, using medical record data from 69 patients treated at a tertiary referral center between 2005 and 2011. All patients underwent laparoscopy; deep detrusor involvement was found in 65.2%, with partial cystectomy for full-thickness lesions in 21 patients and resection or coagulation/ablation for superficial or non-invading nodules in the remaining patients. Over a median follow-up of 60 months (range 4–92), 92.7% of patients were asymptomatic or reported improved urinary symptoms, and no intraoperative complications were reported. The main limitation explicitly reflected in the design is that outcomes come from a retrospective chart review without a non-surgical comparator, and follow-up duration varied. This paper is centrally about endometriosis — it reports long-term outcomes of laparoscopic management specifically for deep bladder endometriosis, including detrusor invasion and full-thickness nodules, which directly relates to endometriosis (and by extension the deep infiltrating phenotype sometimes discussed alongside adenomyosis).

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Abstract

ObjectiveTo assess the efficacy and safety of laparoscopic treatment of bladder endometriosis, especially in cases of full thickness endometriotic nodules.DesignRetrospective review of medical records.SettingTertiary medical center and a referral center for endometriosis.PopulationSixty-nine patients with bladder endometriosis that underwent surgery between January 2005 and December 2011.MethodsThe records of all patients with bladder endometriosis were reviewed and the pre-, intra- and postoperative information of patients who underwent surgery was collected.Main outcome measuresEfficacy, safety and long-term outcome of laparoscopic treatment of bladder endometriosis.ResultsThe mean age of 69 patients with bladder endometriosis was 31.3 ± 4.6 years. Preoperative urinary symptoms (such as frequency, urgency, dysuria and others) were present in 28 (40.0%) patients. Laparoscopy was performed in all patients. Deep detrusor involvement was found in 45 (65.2%) patients. Of these, 21 patients underwent partial cystectomy due to a full thickness lesion. Deep nodule resection without bladder invasion was performed in 24 (34.8%) patients and bladder nodule coagulation and ablation in the remaining 24 (34.8%) patients with superficial involvement. No intraoperative complications were noted. Postoperative follow-up results were available for all patients. After a median (range) follow-up period of 60 (4-92) months, 92.7% of the patients were asymptomatic or reported improvement in symptoms.ConclusionsAfter a long-term follow-up surgical management of bladder endometriosis is strongly recommended. During surgery, careful inspection and full excision of bladder lesions should be performed. Laparoscopic excision is a safe and efficacies approach.
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Abstract

Objective To assess the efficacy and safety of laparoscopic treatment of bladder endometriosis, especially in cases of full thickness endometriotic nodules. Design Retrospective review of medical records. Setting Tertiary medical center and a referral center for endometriosis. Population Sixty-nine patients with bladder endometriosis that underwent surgery between January 2005 and December 2011.

Methods

The records of all patients with bladder endometriosis were reviewed and the pre-, intra- and postoperative information of patients who underwent surgery was collected. Main outcome measures Efficacy, safety and long-term outcome of laparoscopic treatment of bladder endometriosis.

Results

The mean age of 69 patients with bladder endometriosis was 31.3 ± 4.6 years. Preoperative urinary symptoms (such as frequency, urgency, dysuria and others) were present in 28 (40.0 %) patients. Laparoscopy was performed in all patients. Deep detrusor involvement was found in 45 (65.2 %) patients. Of these, 21 patients underwent partial cystectomy due to a full thickness lesion. Deep nodule resection without bladder invasion was performed in 24 (34.8 %) patients and bladder nodule coagulation and ablation in the remaining 24 (34.8 %) patients with superficial involvement. No intraoperative complications were noted. Postoperative follow-up results were available for all patients. After a median (range) follow-up period of 60 (4–92) months, 92.7 % of the patients were asymptomatic or reported improvement in symptoms.

Conclusions

After a long-term follow-up surgical management of bladder endometriosis is strongly recommended. During surgery, careful inspection and full excision of bladder lesions should be performed. Laparoscopic excision is a safe and efficacies approach. Similar content being viewed by others

References

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Condition tags

dyspareuniaendometriosis

MeSH descriptors

Endometriosis Laparoscopy Urinary Bladder Diseases Adult Aged Cystectomy Cystectomy Dyspareunia Dyspareunia Dysuria Dysuria Endometriosis Endometriosis Female Follow-Up Studies Humans Laparoscopy Middle Aged Retrospective Studies Treatment Outcome

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