Effect of Anterior Compartment Endometriosis Excision on Infertility

Gabriele Centini, Karolina Afors, Joao Alves, João Alves, I Argay, István Máté Argay, Philippe R Koninckx, Lucia Lazzeri, Giorgia Monti, Errico Zupi, Arnaud Wattiez
JSLS : Journal of the Society of Laparoendoscopic Surgeons · 2018 · vol. 22(4) , pp. e2018.00067 · doi:10.4293/jsls.2018.00067 · PMID:30662252 · PMC6328363 · W2915052076
article OA: gold CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Laparoscopic excision of anterior compartment endometriosis restored fertility in 44% of women with otherwise-unexplained infertility and resolved symptoms in 84.2% with a low recurrence rate.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 ⓘ

This multicentre retrospective study evaluated reproductive outcomes in 55 women under 40 years old with otherwise-unexplained primary infertility who underwent laparoscopic excision of histologically confirmed deep infiltrating endometriosis involving the anterior pelvic compartment, with follow-up by outpatient visits and telephone interviews 12–24 months after surgery. Pregnancy was achieved by 47.2% of participants overall, including 44% (11/25) in those with anterior disease only and 50% (15/30) when anterior disease was associated with posterior compartment lesions, with 80.7% of pregnancies resulting in live birth and a reported miscarriage rate of 55.5% after ART and 0% after spontaneous conception. The paper does not provide a clearly stated limitation in the provided text section but relies on retrospective design and telephone follow-up, and it excluded concomitant endometrioma treatment at surgery and other infertility factors. This paper is centrally about endometriosis — specifically, the effect of laparoscopic excision of anterior compartment deep infiltrating endometriosis on fertility in otherwise-unexplained infertility.

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Abstract

BACKGROUND AND OBJECTIVES: Laparoscopic surgical excision of bladder nodules has been demonstrated to be effective in relieving associated painful symptoms; the data are lacking concerning the impact of anterior compartment endometriosis on infertility. We conducted this study to evaluate whether or not the surgical excision of deep endometriosis affecting the anterior compartment plays a role in restoring fertility. METHODS: This multicentre, retrospective study included a group of 55 patients presenting with otherwise-unexplained infertility who had undergone laparoscopic excision of anterior compartment endometriosis with histological confirmation. Patient medical records and operative reports were reviewed. Telephone interviews were conducted for long-term followup of fertility outcomes. RESULTS: The pregnancy rate following surgical excision of endometriotic lesions was 44% (n = 11) among those with anterior compartment involvement alone and 50% (n = 15) in case of posterior lesions association without any significant difference. The symptoms related to bladder endometriosis resolved in the 84.2% of the cases with a recurrence rate of 1.8% at the 2-year followup not requiring further surgery. CONCLUSION: Laparoscopic excision of anterior compartment endometriosis is effective in restoring fertility in patients with otherwise-unexplained infertility and in treating endometriosis-related symptoms.

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Condition tags

endometriosisbladder_endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Infertility, Female Pregnancy Rate Adult Endometriosis Female Humans Infertility, Female Laparoscopy Pregnancy Retrospective Studies

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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