Leiomyomatosis Peritonealis Disseminata Associated with Endometriosis and Multiple Uterus-Like Mass: Report of Two Cases

Filomena M Carvalho, Filomena Marino Carvalho, Jesus Paula Carvalho, Ricardo Pereira, Ricardo Mendes Alves Pereira, Benito Pio Vitório Ceccato, Rafael Lacordia, Edmund Chada Baracat
Clinical medicine insights. Case reports · 2012 · vol. 5 , pp. 63–8 · doi:10.4137/ccrep.s9530 · PMID:22661902 · PMC3364027 · W1990390693
article OA: gold CC0 ⤵ 9 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This report describes two cases of leiomyomatosis peritonealis disseminata associated with endometriosis and uterus-like masses, suggesting an endometriotic origin for the condition.

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Abstract

Leiomyomatosis peritonealis disseminate (LPD) is a rare benign disease of unknown etiology of women in reproductive age. A few reported cases of association with endometriosis have been described suggesting a possible origin from submesothelial multipotential cells. We present two cases of LPD associated with endometriosis expressing smooth muscle metaplasia, and some of the nodules with aspects of uterus-like mass. Laparoscopy, gross findings, and the pathological and immunohistochemical study of the surgical specimens were described. Our findings suggest an endometriotic origin for the LPD and indicate that the therapeutic approach might contemplate the surgical reduction of the nodules and endometriosis treatment.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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