Leiomyomatosis Peritonealis Disseminata, Endometriosis, and Multicystic Mesothelioma

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Abstract

A 32-year-old, previously healthy woman with a diffuse, complex tumoral process is described. While she was being evaluated for primary infertility, a laparoscopic procedure revealed a disseminated peritoneal process associated with bilateral ovarian lesions. A clinical diagnosis of stage III ovarian cancer was made and total hysterectomy, bilateral salpingo-oophorectomy, and omentectomy were performed. Pathologic studies showed an admixture of leiomyomatosis peritonealis disseminata (LPD) endometriosis, and an extensive multicystic mesothelial proliferation. Although endometriosis is known to occur in conjunction with either LPD or multicystic mesothelioma, to our knowledge this is the first report of all three lesions occurring simultaneously.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Leiomyomatosis Mesothelioma, Cystic Peritoneal Neoplasms Adult Diagnosis, Differential Endometriosis Endometriosis Endometriosis Female Humans Leiomyomatosis Leiomyomatosis Leiomyomatosis Mesothelioma, Cystic Mesothelioma, Cystic Mesothelioma, Cystic Ovarian Neoplasms Peritoneal Neoplasms Peritoneal Neoplasms

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europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:10:40.754221+00:00
License: CC0 · commercial use OK