Leiomyomatosis peritonealis disseminata presenting with intravascular extension and coexisting with endometriosis: a case report.

Ali Haberal, Alı Haberal, Fulya Kayikcioglu, Fulya Kayıkçıoğlu, Gamze Sinem Çağlar, Gamze Sinem Caglar, Deniz Cavusoglu, Deniz Çavuşoğlu
The Journal of reproductive medicine · 2007 · vol. 52(5) , pp. 422–4 · PMID:17583244 · W2411286116
article OA: closed CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes leiomyomatosis peritonealis disseminata with intravascular extension and coexisting endometriosis in a 46-year-old woman, highlighting the increased mortality risk associated with intravascular spread.

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Abstract

BACKGROUND: Leiomyomatosis peritonealis disseminata is a benign disease of women of reproductive age. Female gonadal steroids play the major role in pathogenesis, but reported cases in postmenopausal women suggests other factors. A few cases in the literature with coexisting endometriosis confirm the hypothesis that both originate in submesothelial multipotential mesenchymal cells. The clinical behavior can be life threatening due to extension through the pelvic veins. CASE: A 46-year-old woman with endometriosis diagnosed at laparotomy 3 years earlier presented with a huge pelvic mass. Postoperative histologic examination of the peritoneal nodules confirmed the diagnosis. Magnetic resonance angiography performed postoperatively revealed intravenous leiomyomatosis. Surgical castration was satisfactory after 2 years of follow-up. CONCLUSION: Although malignant transformation of the disease is known, intravascular extension of the tumor increases the risk of mortality. Close follow-up by clinical examination and radiologic evaluations is required.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Leiomyomatosis Peritoneal Neoplasms Appendectomy Diagnosis, Differential Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Hysterectomy Leiomyomatosis Leiomyomatosis Leiomyomatosis Leiomyomatosis Magnetic Resonance Imaging Middle Aged Ovariectomy Peritoneal Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (6)

Cited by (6)

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