Maintenance therapy involving a tapering dose of danazol or mid/low doses of oral contraceptive after gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain

Jo Kitawaki, Kitawaki J, Hiroaki Ishihara, Ishihara H, Miyo Kiyomizu, Kiyomizu M, Hideo Honjo, Honjo H
Fertility and sterility · 2007 · vol. 89(6) , pp. 1831–1835 · doi:10.1016/j.fertnstert.2007.05.052 · PMID:17761178 · W2060015859
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study compared maintenance therapies with tapering danazol or oral contraceptives after GnRH agonist treatment for endometriosis-associated pelvic pain.

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Abstract

Pelvic pain associated with endometriosis was treated by the long-term administration of a tapering dose of danazol or mid/low doses of oral contraceptives after the end of therapy involving a GnRH agonist (GnRH-a). Results demonstrated that each of these three therapies is a practical and efficient treatment regimen to maintain the relief of pelvic pain achieved by GnRH-a therapy, at least for a period of 12 months.

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Condition tags

dysmenorrheaendometriosischronic_pelvic_pain

MeSH descriptors

Contraceptives, Oral Danazol Endometriosis Estrogen Antagonists Gonadotropin-Releasing Hormone Pelvic Pain CA-125 Antigen CA-125 Antigen CA-125 Antigen Contraceptives, Oral Contraceptives, Oral Danazol Danazol Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Endometriosis Estrogen Antagonists

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (20)

Cited by (21)

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