Cytologic diagnosis of peritoneal fluids. Applicability to the laparoscopic diagnosis of endometriosis
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⤵ 12 in-corpus citations
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Cytologic examination of laparoscopic peritoneal fluid identified endometrial cells and hemosiderin-laden macrophages, with the latter being more specific for diagnosing endometriosis.
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Abstract
OBJECTIVE: To determine the accuracy of cytologic examination of laparoscopically obtained peritoneal fluid in the diagnosis of endometriosis.
STUDY DESIGN: This investigation analyzed 50 laparoscopic fluid specimens received over a three-year period. Retrospective cytologic findings were correlated with clinical history and laparoscopic diagnoses. Touch preparations were also collected from necropsies to develop cytologic criteria necessary to distinguish endometrial cells from mesothelial cells.
RESULTS: The presence of hemosiderin-laden macrophages in peritoneal fluids was more specific but less sensitive than the presence of endometrial cells for the diagnosis of endometriosis.
CONCLUSIONS: In women undergoing laparoscopy to detect endometriosis, the identification of endometrial cells alone in peritoneal fluids may not be sufficient to render a definitive diagnosis of endometriosis. However, the presence of hemosiderin-laden macrophages in this population should alert the cytologist to that possibility.
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References (14)
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Cited by (10)
- Peritoneal lavage cytology in the diagnosis of pelvic endometriosis 2021
- Gross Ascites Secondary to Endometriosis: A Rare Presentation in Pre-Menopausal Women 2021
- Endometriosis in Peritoneal Washings–A Potential Diagnostic Pitfall in a Patient with Known Endometrial Adenocarcinoma 2016
- The Presence of Endometrial Cells in Peritoneal Fluid of Women With and Without Endometriosis 2016
- Role of Iron in the Pathogenesis of Endometriosis 2015
- Endosalpingiosis in peritoneal washings in women with benign gynecologic conditions: thirty-eight cases confirmed with paired box-8 immunohistochemical staining and correlation with surgical biopsy findings 2013
- The role of diagnostic laparoscopy for chronic abdominal conditions: an evidence-based review 2009
- Peritoneal washing cytology 2004
- Iron overload in the peritoneal cavity of women with pelvic endometriosis 2002
- Oxidative stress and peritoneal endometriosis 2002
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- europepmc
- last seen: 2026-10-14T06:08:39.101224+00:00
- openalex
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- pubmed
- last seen: 2026-10-08T22:00:16.042305+00:00
- unpaywall
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