Cytology of peritoneal washings in gynecologic patients. Diagnostic criteria and pitfalls.

E Ravinsky, Esther Ravinsky, Ravinsky E
Acta cytologica · 1986 · vol. 30(1) , pp. 8–16 · PMID:3456188 · W2416926278
article OA: closed CC0 ⤵ 11 in-corpus citations
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This study reviewed peritoneal washings from 226 gynecologic patients, detailing diagnostic criteria and pitfalls in distinguishing reactive mesothelium from malignancy and benign from malignant ovarian lesions.

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Abstract

A total of 226 peritoneal washing specimens obtained from gynecologic patients over a three-year period was reviewed. The diagnostic problems encountered were: differentiating reactive mesothelium from low-grade malignancies; distinguishing between benign ovarian tumors, ovarian tumors of borderline malignancy and low-grade ovarian malignancies; and potential false-positive diagnoses in endometriosis. Low-grade malignancies could be distinguished from reactive mesothelium by evaluating subtle cytologic criteria and by comparing the cells to those of the tumor on histologic section. The differentiation of low-grade epithelial malignancies from benign epithelial lesions caused difficulties that could only be resolved by evaluating the histologic material. Positive peritoneal washings increased the stage in 8 of 110 patients undergoing initial surgery for gynecologic malignancy. Two of 76 patients undergoing a second-look laparotomy had positive washings without histologic evidence of tumor. These ten patients did less well than did those with similar histology but negative washing cytology, despite receiving additional therapy because of the cytologic findings.

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Condition tags

endometriosis

MeSH descriptors

Genital Neoplasms, Female Peritoneum Adnexal Diseases Adnexal Diseases Adnexa Uteri Adnexa Uteri Endometriosis Endometriosis Female Genital Neoplasms, Female Genital Neoplasms, Female Humans Neoplasm Staging Ovarian Neoplasms Ovarian Neoplasms Peritoneum Therapeutic Irrigation Uterine Neoplasms Uterine Neoplasms

Citation neighborhood

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Cited by (11)

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License: CC0 · commercial use OK