Cytologic Diagnosis of Peritoneal Fluids

Susan B. Stowell, Stowell SB, S B Stowell, Wiley CM, Christina M. Wiley, C M Wiley, Perez-Reyes N, N Perez-Reyes, Nuria Perez‐Reyes, Powers CN, Celeste N. Powers, C N Powers
Acta cytologica · 1997 · vol. 41(3) , pp. 817–822 · doi:10.1159/000332709 · PMID:9167707 · W2080332170
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Cytologic examination of laparoscopic peritoneal fluid identified endometrial cells and hemosiderin-laden macrophages, with the latter being more specific for diagnosing endometriosis.

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Abstract

OBJECTIVE: To determine the accuracy of cytologic examination of laparoscopically obtained peritoneal fluid in the diagnosis of endometriosis. STUDY DESIGN: This investigation analyzed 50 laparoscopic fluid specimens received over a three-year period. Retrospective cytologic findings were correlated with clinical history and laparoscopic diagnoses. Touch preparations were also collected from necropsies to develop cytologic criteria necessary to distinguish endometrial cells from mesothelial cells. RESULTS: The presence of hemosiderin-laden macrophages in peritoneal fluids was more specific but less sensitive than the presence of endometrial cells for the diagnosis of endometriosis. CONCLUSIONS: In women undergoing laparoscopy to detect endometriosis, the identification of endometrial cells alone in peritoneal fluids may not be sufficient to render a definitive diagnosis of endometriosis. However, the presence of hemosiderin-laden macrophages in this population should alert the cytologist to that possibility.

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Uterine Diseases Adult Ascitic Fluid Endometriosis Female Hemosiderin Hemosiderin Humans Laparoscopy Macrophages Macrophages Male Middle Aged Retrospective Studies Sensitivity and Specificity Uterine Diseases

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