False-positive malignant peritoneal cytology associated with pelvic endometriosis

Sotirios N. Markuly, S N Markuly, Markuly SN, James Fanning, Fanning J, J Fanning, Travis L. Hindman, Hindman TL, T L Hindman, Phillip C. Galle, Galle PC, P C Galle, Peter R. Galle, E Ertmoed, Ertmoed E, Ernest Ertmoed, Hilgers RD, R D Hilgers, Robert D. Hilgers
The Journal of the American Osteopathic Association · 1994 · vol. 94(2) , pp. 157 · doi:10.7556/jaoa.1994.94.2.157 · PMID:8200821 · W53879816
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This paper presents two cases of endometriosis mimicking malignant peritoneal cytology and reviews literature on false-positive malignancy assessments.

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Abstract

The peritoneal washings obtained at diagnostic laparoscopy of two women with suspected endometriosis contained cells with cytologic features of adenocarcinoma. Exploratory laparotomy, total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and pelvic washings confirmed endometriosis with no evidence of cancer. At 1.5-year and 4.0-year follow-up, respectively, cancer had not developed in either patient. The authors report what they were able to find in the literature regarding false-positive assessments of malignancy obtained by cytologic examination. They also outline steps to be taken should a diagnosis of malignancy arise in a woman with endometriosis who desires pregnancy.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Peritoneal Lavage Adenocarcinoma Adenocarcinoma Adult Diagnosis, Differential Diagnostic Errors Endometriosis Endometriosis False Positive Reactions Female Follow-Up Studies Genital Neoplasms, Female Genital Neoplasms, Female Humans Laparoscopy Middle Aged Ovarian Diseases Ovarian Diseases

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License: CC0 · commercial use OK