False-positive malignant peritoneal cytology associated with pelvic endometriosis

Sotirios N. Markuly, S N Markuly, Markuly SN, James Fanning, Fanning J, J Fanning, Travis L. Hindman, Hindman TL, T L Hindman, Phillip C. Galle, Galle PC, P C Galle, Peter R. Galle, E Ertmoed, Ertmoed E, Ernest Ertmoed, Hilgers RD, R D Hilgers, Robert D. Hilgers
The Journal of the American Osteopathic Association · 1994 · vol. 94(2) , pp. 157 · doi:10.7556/jaoa.1994.94.2.157 · PMID:8200821 · W53879816
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This paper presents two cases of endometriosis mimicking malignant peritoneal cytology and reviews literature on false-positive malignancy assessments.

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Abstract

The peritoneal washings obtained at diagnostic laparoscopy of two women with suspected endometriosis contained cells with cytologic features of adenocarcinoma. Exploratory laparotomy, total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and pelvic washings confirmed endometriosis with no evidence of cancer. At 1.5-year and 4.0-year follow-up, respectively, cancer had not developed in either patient. The authors report what they were able to find in the literature regarding false-positive assessments of malignancy obtained by cytologic examination. They also outline steps to be taken should a diagnosis of malignancy arise in a woman with endometriosis who desires pregnancy.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Peritoneal Lavage Peritoneal Lavage Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Adult Diagnosis, Differential Diagnosis, Differential Diagnostic Errors Diagnostic Errors Endometriosis Endometriosis Endometriosis False Positive Reactions False Positive Reactions Female Female

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License: CC0 · commercial use OK