Malignancy Risks Associated with Endometriosis: Epidemiology
This paper presents a meta-analysis of studies up to 2019 on endometriosis and cancer risk, discussing research complexities, potential mechanisms, and management recommendations.
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This epidemiology-focused chapter summarizes and discusses evidence from epidemiologic studies and a meta-analysis (through 2019) quantifying cancer risk in people with endometriosis. It highlights methodological complexities that complicate interpretation of associations between endometriosis and malignancy, and it also reviews proposed mechanisms. The chapter includes recommendations related to patient information, cancer screening considerations, and long-term management of endometriosis patients in relation to cancer risk, with an explicit caveat that the field’s methodology affects how findings should be understood. This paper is centrally about endometriosis — it reviews epidemiologic malignancy risk associations and the complexities of interpreting cancer risk in endometriosis.
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References (45)
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