Characterization of endometrial mesenchymal stem-like cells obtained by endometrial biopsy during routine diagnostics
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⤵ 26 in-corpus citations
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This paper characterizes endometrial mesenchymal stem-like cells isolated from endometrial biopsies taken during routine diagnostic procedures.
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Abstract
Endometrial cell clones derived from in vitro cultured purified stromal cells obtained by endometrial biopsy display characteristic stem cell features, including clonality; long-term culturing properties; multilineage differentiation potential; expression of CD146, CD105, CD90, CD73, MSI1, NOTCH1, and SOX2; and absence of CD34 and CD14 expression. We conclude that adult stem cells are present in endometrial biopsies performed in a routine clinical setting, offering new large-scale approaches for future research, diagnostics, and therapies involving adult stem cells.
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References (25)
- Clonogenicity of human endometrial epithelial and stromal cells via openalex
- Dating the Endometrial Biopsy via openalex
- Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma via openalex
- Multitasking human endometrium: a review of endometrial biopsy as a diagnostic tool, therapeutic applications, and a source of adult stem cells via openalex
- Putative stem cell activity of human endometrial epithelial and stromal cells during the menstrual cycle via openalex
- Stammzellen im Endometrium via openalex
- Uterine stem cells: what is the evidence? via openalex
- W2056936400 via openalex
- W2079224311 via openalex
- W2079737009 via openalex
- W2107277218 via openalex
- W2135798800 via openalex
- W2138977668 via openalex
- W2143516059 via openalex
- W2146710021 via openalex
- W2152492124 via openalex
- W2159999899 via openalex
- W70858774 via openalex
- W6632328943 via openalex
- W1505585050 via openalex
- W1540826485 via openalex
- W2002963491 via openalex
- W2012925048 via openalex
- W2013074450 via openalex
- W2025371271 via openalex
Cited by (26)
- Combined targeting of TCF7L1/2, PTEN, CDK6, and BCCIP by microRNA miR-29c-3p is associated with reduced invasion and proliferation of endometriotic cells 2025
- Sox-2 positive cells identified in lymph nodes from endometriosis patients may play a role in the disease pathogenesis 2023
- Long-term maintenance of human endometrial epithelial organoids and their stem cell properties 2023
- The perivascular niche of endometrial mesenchymal stromal/stem-like cells 2022
- Impact of Musashi-1 and Musashi-2 Double Knockdown on Notch Signaling and the Pathogenesis of Endometriosis 2022
- Resveratrol impairs cellular mechanisms associated with the pathogenesis of endometriosis 2022
- Expression of Fucosyltransferase 4 (FUT4) mRNA Is Increased in Endometrium from Women with Endometriosis 2022
- The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro 2021
- Adenomyosis: Mechanisms and Pathogenesis 2020
- miR-142-3p Reduces the Size, Migration, and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-Related Pathways That Regulate Cytoskeletal Function 2020
- miR-142-3p Reduces the Size, Migration and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-related Pathways that Regulate Cytoskeletal Function 2020
- γ-Secretase inhibition affects viability, apoptosis, and the stem cell phenotype of endometriotic cells 2019
- Regulation of Proliferation and Invasion in Endometriosis 2019
- Therapeutic strategies involving uterine stem cells in reproductive medicine 2018
- Endometrial Stem Cell Markers: Current Concepts and Unresolved Questions 2018
- Seminal plasma (SP) induces a rapid transforming growth factor beta 1 (TGFβ1)-independent up-regulation of epithelial-mesenchymal transdifferentiation (EMT) and myofibroblastic metaplasia-markers in endometriotic (EM) and endometrial cells 2018
- The Fate of Autologous Endometrial Mesenchymal Stromal Cells After Application in the Healthy Equine Uterus 2018
- Cells with “Stemness”: Seeds for endometriosis? 2016
- microRNA miR-200b affects proliferation, invasiveness and stemness of endometriotic cells by targeting ZEB1, ZEB2 and KLF4 2016
- The Role of Stem Cells in the Etiology and Pathophysiology of Endometriosis 2015
- Stem cells in endometrium and endometriosis 2015
- Endometriosis: Are Stem Cells Involved? 2015
- Regenerating endometrium from stem/progenitor cells: is it abnormal in endometriosis, Asherman's syndrome and infertility? 2013
- Endometrial regeneration and endometrial stem/progenitor cells 2012
- Targeting of syndecan-1 by micro-ribonucleic acid miR-10b modulates invasiveness of endometriotic cells via dysregulation of the proteolytic milieu and interleukin-6 secretion 2012
- MicroRNAs and the pathogenesis of endometriosis 2012
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- last seen: 2026-06-10T17:14:06.276822+00:00
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- last seen: 2026-10-08T21:08:04.945943+00:00
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- last seen: 2026-09-17T06:32:46.214484+00:00
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