Coexistence of adenomyosis in women operated for benign gynecological diseases

Zehra Sema Özkan, Kumbak B, Banu Kumbak, Cilgin H, Hasan Cilgin, Hasan Çılgın, Mehmet Simsek, Mehmet Şimşek, Simsek M, Bilge Aydın Türk, Bilge Aydin Turk, Turk BA
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2011 · vol. 28(3) , pp. 212–215 · doi:10.3109/09513590.2011.593669 · PMID:21827379 · W2160332481
Observational OA: closed CC0 ⤵ 12 in-corpus citations
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This study compared women with adenomyosis to those with leiomyoma, finding adenomyosis patients were older with higher parity and a history of endometrial sampling, suggesting this procedure may trigger adenomyosis.

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Abstract

BACKGROUND: To compare demographic, clinical and histopathological characteristics of women diagnosed with adenomyosis (AG) after hysterectomy to those of women diagnosed with leiomyoma (LG) and to investigate the predisposing factors for AG. METHODS: This study was carried out on 204 patients who underwent gynecologic surgery for various indications except for gynecologic malignancy between January 2005 and December 2009 and whose histopathological analysis of hysterectomy/myomectomy specimen revealed either AG or LG. Women with AG and those with LG were compared with respect to age, parity, menstrual pattern, history of induced abortion, history of prior uterine surgery, smoking, dysmenorrhea, dyspareunia, chronic pelvic pain and coexisting endometrial and ovarian pathologies. RESULTS: The mean age of our patients was 51 ± 8 years (range 28-85), 40% of them were postmenopausal, and 64% had a history of uterine surgery. The mean age (p = 0.014), gravida (p = 0.018), parity (p = 0.017) and previous endometrial sampling (p < 0.01) were significantly higher in AG. Main symptoms were abnormal uterine bleeding (39%), dysmenorrhea (63%) and nonmenstrual pelvic pain (62%). Age (p = 0.01), menometrorrhagia (p = 0.02) and endometrial sampling (p < 0.01) were the significant covariants in binary logistic regression for AG. CONCLUSION: AG is an enigmatic disease frequently causing gynecologic complaints and endomyometrial junction deterioration during endometrial sampling may be a trigger point for developing AG.

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Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_painadenomyosis

MeSH descriptors

Endometriosis Endometriosis Genital Diseases, Female Genital Diseases, Female Hysterectomy Hysterectomy Adult Adult Aged Aged Aged, 80 and over Aged, 80 and over Dysmenorrhea Dysmenorrhea Dyspareunia Dyspareunia Endometriosis Endometriosis Endometrium Endometrium

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (26)

Cited by (12)

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