Adenomyosis

Paolo Vercellini, Vercellini P, P Vercellini, G. Ragni, Ragni G, Trespidi L, L Trespidi, Laura Trespìdi, S Oldani, Oldani S, Sabina Oldani, S Panazza, Panazza S, Stefania Panazza, Pier Giorgio Crosignani, P. G. Crosignani, Crosignani PG
Obstetrical & gynecological survey · 1993 · vol. 48(12) , pp. 789–794 · doi:10.1097/00006254-199312000-00004 · PMID:8309661 · W2087203471
article OA: closed CC0 ⤵ 39 in-corpus citations
Full text JSON View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-10 ⓘ

Adenomyosis, historically diagnosed post-hysterectomy, is now more accurately detected in situ, potentially clarifying its epidemiology and pathogenic role in gynecological symptoms.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-13 · read from full text ⓘ

This review article examines the diagnostic challenges and clinical significance of adenomyosis, noting that previous studies were limited by selection biases and reliance on post-hysterectomy histopathology. The authors highlight the emergence of accurate in situ diagnostic techniques which may clarify the condition's epidemiology and its potential pathogenic role in menorrhagia and dysmenorrhea. They also discuss resectoscopic treatment as a uterine-sparing option for mild cases while emphasizing the need for standardized histologic criteria to determine if adenomyosis is a distinct disease or a physiological variant. This paper is centrally about adenomyosis, focusing on diagnostic criteria, clinical presentation, and management strategies for this specific uterine disorder.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Adenomyosis is a relatively frequent finding in series of hysterectomies performed for menorrhagia and dysmenorrhea. Evident selection biases of the available studies on adenomyosis have always limited the possibilities of defining the real clinical importance of the condition. Until now the only certain diagnoses have been made by histopathologists on uteri removed at surgery, but recently various sufficiently accurate techniques have been suggested which allow diagnosis on the uterus in situ. With the these methods it might be possible to obtain correct information on the epidemiologic characteristics of adenomyosis and to clarify whether it has a pathogenic role in unexplained ovulatory menorrhagia and juvenile dysmenorrhea. Furthermore, resectoscopic treatment has been proposed in some mild forms of adenomyosis to avoid hysterectomy, whereas it seems improbable that medical treatment can offer a definitive solution. The adoption of standard histologic criteria for adenomyosis seems important. Until this is done, it will be difficult to establish whether adenomyosis is really a disease or merely a paraphysiologic condition.
Full text 1,278 characters · extracted from oa-doi-fallback · click to expand
Adenomyosis A Déjà Vu? - Paolo Vercellini - Guido Ragni - Laura Trespidi - Sabina Oldani - Stefania Panazza - Pier Giorgio Crosignani Adenomyosis is a relatively frequent finding in series of hysterectomies performed for menorrhagia and dysmenorrhea. Evident selection biases of the available studies on adenomyosis have always limited the possibilities of defining the real clinical importance of the condition. Until now the only certain diagnoses have been made by histopathologists on uteri removed at surgery, but recently various sufficiently accurate techniques have been suggested which allow diagnosis on the uterus in situ. With the these methods it might be possible to obtain correct information on the epidemiologic characteristics of adenomyosis and to clarify whether it has a pathogenic role in unexplained ovulatory menorrhagia and juvenile dysmenorrhea. Furthermore, resectoscopic treatment has been proposed in some mild forms of adenomyosis to avoid hysterectomy, whereas it seems improbable that medical treatment can offer a definitive solution. The adoption of standard histologic criteria for adenomyosis seems important. Until this is done, it will be difficult to establish whether adenomyosis is really a disease or merely a paraphysiologic condition.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

dysmenorrheaendometriosisadenomyosis

MeSH descriptors

Dysmenorrhea Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Menorrhagia Uterine Diseases Uterine Diseases Uterine Diseases Uterine Diseases Uterine Diseases Uterine Diseases Adult Aged Age Factors Biopsy Dysmenorrhea Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (38)

Source provenance

europepmc
last seen: 2026-09-10T06:15:44.054944+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:11:34.315996+00:00
License: CC0 · commercial use OK