Oxidative stress and female reproductive disorder

Kalaivani Manokaran, Kumar M. R. Bhat, Pavithra Bhat, Deepak Nayak M, Ravisankar Baskaran, R. Baskaran, Prabu Paramasivam, Shiek Fareeth Ahmed, Keerthi Priya, K. Sreedhara Ranganath Pai, Vignesh E Balaji
In: Asian Pacific Journal of Reproduction · 2022 · vol. 11(3) , pp. 107–116 · doi:10.4103/2305-0500.346088 · W4285251653
review OA: diamond CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review examines how oxidative stress contributes to female reproductive disorders like infertility and PCOS, and highlights vitamin C's protective role in alleviating these effects.

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Abstract

Oxidative stress arises from an imbalance between the body's pro-oxidants and antioxidants. Recently, oxidative stress has been proven a contributing factor to many female reproductive disorders including infertility, preeclampsia, endometriosis and polycystic ovarian syndrome. Herein, we review the mechanistic role of oxidative stress in inducing the most common female reproductive disorders. The current review has also highlighted the protective role of vitamin C, necessary for certain female reproductive hormone secretion by the antral follicle and corpus luteum and also essential for collagen production in ovarian tissue remodeling after ovulation, in alleviating oxidative stress and thus improving female reproductive outcomes.

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endometriosisinfertility

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last seen: 2026-06-10T17:14:06.276822+00:00
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