Endometriosis-associated Clear Cell Carcinoma of the Abdominal Wall After Caesarean Section: A Case Report and Review of the Literature

Luca Giannella, Matteo Serri, Elena Maccaroni, Jacopo Di Giuseppe, Giovanni Delli Carpini, Rossana Berardi, Francesco Sopracordevole, Andrea Ciavattini
In vivo (Athens, Greece) · 2020 · vol. 34(4) , pp. 2147–2152 · doi:10.21873/invivo.12021 · PMID:32606196 · W3039514827
review OA: diamond CC0 ⤵ 12 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report and literature review describes a rare clear cell carcinoma of the abdominal wall arising from endometriosis following a cesarean section, with a poor prognosis and high mortality rate.

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Abstract

BACKGROUND/AIM: Clear cell carcinoma of the abdominal wall is a sporadic event. To date, about thirty cases have been reported in the literature. This article provides a case report and literature review of an infrequent occurrence with poor prognosis. CASE REPORT: A 45-year-old woman with pelvic pain and an abdominal mass came to our attention. Her medical history was notable for two previous cesarean sections. Physical examination revealed a smooth, multilocular mass measuring about 20 cm, arising from the previous surgical scar. Histology revealed clear-cell carcinoma resulting from the transformation of abdominal wall endometriosis. Given the disease extent, the patient underwent front-line chemotherapy. After several and multiple chemotherapy regimens, there was a disease progression that resulted in the death of the patient in 7 months. The literature review showed that a previous cesarean section was present in 91% of cases. Besides, approximately 26.5% of women died within 12 months of being diagnosed. The mean age of women was 45.88 years, while the average size of the lesion was 11 cm. CONCLUSION: Clear cell carcinoma is a rare but occurring event. Middle-aged women showing an abdominal wall mass in close relation with a surgical scar from a previous cesarean section must be promptly investigated. Treatment options usually include surgery and chemotherapy with poor results.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Abdominal Wall Abdominal Wall Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Endometriosis Endometriosis Cesarean Section Cesarean Section Cicatrix Cicatrix Cicatrix Female Humans Middle Aged Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (44)

Cited by (12)

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License: CC0 · commercial use OK