Endometriosis: absence of recurrence in patients after endometrial ablation

Carlo Bulletti, C Bulletti, Bulletti C, DeZiegler D, Dominique DeZiegler, D. DeZiegler, Stefanetti M, Marco Stefanetti, M. Stefanetti, Cicinelli E, E. Cicinelli, Ettore Cincinelli, Emanuele Pelosi, E. Pelosi, Flamigni C, C Flamigni
Human Reproduction · 2001 · vol. 16(12) , pp. 2676–2679 · doi:10.1093/humrep/16.12.2676 · PMID:11726595 · W2130520180
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Endometrial ablation reduced endometriosis recurrence by preventing the tubal dissemination of endometrial debris and implantation of endometrial cells into the abdomen.

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Abstract

BACKGROUND: The present study was undertaken to evaluate differences between patients with and without eutopic endometrium in the recurrence of ectopic endometriotic implants. METHODS: Endometrial ablation (EA) was carried out in 14 women out of 28 laparoscopically treated for endometriosis and recurrence of the disease was evaluated 24 months later. Data were compared using paired Student's t-test and chi2 test. RESULTS: Patients undergoing EA procedures did not exhibit recurrence of endometriosis while nine patients without that procedure had recurrence of the disease (P < 0.001). The endometrial cells found in the debris of the cul de sac of eight patients who did not undergo EA were both stromal and epithelial cells. No blood or blood cells were found in the cul de sac of patients undergoing EA. CONCLUSIONS: The present study supports a role of eutopic endometrium in the recurrence of endometriosis through tubal dissemination of endometrial debris and implantation of endometrial cells into the abdomen.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Endometriosis Endometrium Laparoscopy Adult Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Endometriosis Endometrium Endometrium Epithelial Cells Epithelial Cells Female Humans Menstrual Cycle Recurrence Second-Look Surgery Stromal Cells Stromal Cells

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