Comparison of the pharmacology of nafarelin and danazol
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⤵ 13 in-corpus citations
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This paper compared the pharmacological effects of nafarelin and danazol, focusing on their mechanisms of action and potential therapeutic applications.
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Abstract
The pharmacologic profiles of danazol and nafarelin differ considerably from each other. Danazol interacts with multiple classes of proteins, whereas the gonadotropin-releasing hormone agonist nafarelin interacts only with the pituitary gonadotropin-releasing hormone receptor. Differences in the molecular, endocrine, and clinical pharmacologic properties of these agents may provide clues to their varying effects in the management of women with endometriosis.
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References (19)
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- Administration of Nasal Nafarelin as Compared with Oral Danazol for Endometriosis via openalex
- Cholesterol, High Density Lipoprotein and Danazol via openalex
- Danazol binding and translocation of steroid receptors via openalex
- Danazol Binding to Rat Androgen, Glucocorticoid, Progesterone, and Estrogen Receptors: Correlation With Biologic Activity via openalex
- Danazol inhibits human adrenal 21-and 11β-hydroxylation invitro via openalex
- Danazol Inhibits Steroidogenesis via openalex
- Danazol inhibits steroidogenesis by the human ovary in vivo via openalex
- Danazol Inhibits Steroidogenesis in the Rat Testis<i>in Vitro</i> via openalex
- Effects of danazol on gonadal steroidogenesis in patients with a complete form of testicular feminization via openalex
- Free testosterone levels during danazol therapy via openalex
- Inhibition of Adrenal Steroidogenesis by Danazol in Vivo via openalex
- Metabolic changes during medical treatment of endometriosis: Nafarelin acetate versus danazol via openalex
- The absorption, distribution and metabolic fate of danazol in rats, monkeys and human volunteers. via openalex
- THE INTERACTION OF HUMAN ENDOMETRIAL AND MYOMETRIAL STEROID RECEPTORS WITH DANAZOL via openalex
- W6712913964 via openalex
- W1618997004 via openalex
- W2129449855 via openalex
- W2409029091 via openalex
Cited by (13)
- Danazol 2022
- INDIVIDUALIZATION OF MANAGEMENT OF PATIENTSWITH ENDOMETRIOSIS OF THE UTERUS BASED ON THE USEOF LEVONORGESTREL-CONTAINING INTRAUTERINE SYSTEMAND HYSTERORESECTOSCOPIC ENDOMETRIAL ABLATION 2017
- Paradigm Shift: The Realization of New Medical Alternatives to Surgery for Endometriosis 2016
- Effects of laparoscopic radical surgery for deep endometriosis on endometriosis-related pelvic pain 2012
- Gonadotropin Releasing Honnone Agonist and Antagonist for Endometriosis 2003
- Controversias en el manejo quirúrgico del endometrioma ovárico 2002
- The inhibitory effect of dienogest, a synthetic steroid, on the growth of human endometrial stromal cells in vitro 2001
- Endometriosis: An Enigmatic Disease 1996
- Endometriosis 1992
- Spontaneous and steroid-induced recurrence of endometriosis after suppression by a gonadotropin-releasing hormone antagonist in the rat 1991
- Medical treatment of endometriosis: a comparison of the suppressive effects of danazol and nafarelin on reproductive hormones 1991
- Goserelin 1991
- Nafarelin 1990
Source provenance
- europepmc
- last seen: 2026-07-30T06:25:42.655704+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:12:10.587122+00:00
- unpaywall
- last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0
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